Literature DB >> 9347858

Transjugular intrahepatic portosystemic shunt versus H-graft portacaval shunt in the management of bleeding varices: a cost-benefit analysis.

A S Rosemurgy1, M Bloomston, E E Zervos, S E Goode, D Pencev, B Zweibel, T J Black.   

Abstract

BACKGROUND: Transjugular intrahepatic portosystemic shunt (TIPS) is popular in treating portal hypertension because of its perceived efficacy and cost benefits, although it has never been compared with surgical shunting in a cost-benefit analysis. This study was undertaken to determine the cost benefit of TIPS versus small-diameter prosthetic H-graft portacaval shunt (HGPCS).
METHODS: Cost of care was determined in 80 patients prospectively randomized to receive TIPS or HGPCS as definitive treatment for bleeding varices, beginning with shunt placement and including subsequent admissions for complications or follow-up related to shunting.
RESULTS: Patients were similar in age, gender, severity of illness/liver dysfunction, and urgency of shunting. After TIPS or HGPCS, variceal rehemorrhage (8 versus O, respectively; p = 0.03), shunt occlusion (13 versus 4; p = 0.03), shunt revision (16 versus 4; p < 0.005), and shunt failure (18 versus 10; p = 0.10) were compared; all were more common after TIPS. Through the index admission, TIPS cost $48,188 +/- $43,355 whereas HGPCS cost $61,552 +/- $47,615. With follow-up, TIPS cost $69,276 +/- $52,712 and HGPCS cost $66,034 +/- $49,118.
CONCLUSIONS: Early cost of TIPS was less than, though not different from, cost of HGPCS. With follow-up, costs after TIPS mounted. The initially lower cost of TIPS is offset by higher rates of subsequent occlusion and rehemorrhage.

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Year:  1997        PMID: 9347858     DOI: 10.1016/s0039-6060(97)90089-1

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  10 in total

1.  Transjugular intrahepatic portosystemic shunt versus H-graft portacaval shunt in the management of bleeding varices: a cost-benefit analysis.

Authors:  Marcelo Enne; Lucio F Pacheco-Moreira; Elizabeth Balbi; José Manoel Martinho
Journal:  Ann Surg       Date:  2006-01       Impact factor: 12.969

2.  Octreotide followed by sclerotherapy was not more effective than emergency injection sclerotherapy for acute variceal haemorrhage.

Authors:  A Burroughs
Journal:  Gut       Date:  1998-07       Impact factor: 23.059

3.  Transjugular intrahepatic portosystemic shunt vs. small-diameter prosthetic H-graft portacaval shunt: extended follow-up of an expanded randomized prospective trial.

Authors:  A S Rosemurgy; F M Serafini; B R Zweibel; T J Black; B T Kudryk; H J Nord; S E Goode
Journal:  J Gastrointest Surg       Date:  2000 Nov-Dec       Impact factor: 3.452

Review 4.  Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis.

Authors:  S Khan; C Tudur Smith; P Williamson; R Sutton
Journal:  Cochrane Database Syst Rev       Date:  2006-10-18

5.  Survival and variceal rehemorrhage after shunting support small-diameter prosthetic H-graft portacaval shunt.

Authors:  Alexander Rosemurgy; Donald Thometz; Whalen Clark; Desiree Villadolid; Elizabeth Carey; Daphne Pinkas; Steven Rakita; Emmanuel Zervos
Journal:  J Gastrointest Surg       Date:  2007-03       Impact factor: 3.452

Review 6.  Current state of portosystemic shunt surgery.

Authors:  Martin Wolff; Andreas Hirner
Journal:  Langenbecks Arch Surg       Date:  2003-03-29       Impact factor: 3.445

7.  Treatment for bleeding oesophageal varices in people with decompensated liver cirrhosis: a network meta-analysis.

Authors:  Danielle Roberts; Lawrence Mj Best; Suzanne C Freeman; Alex J Sutton; Nicola J Cooper; Sivapatham Arunan; Tanjia Begum; Norman R Williams; Dana Walshaw; Elisabeth Jane Milne; Maxine Tapp; Mario Csenar; Chavdar S Pavlov; Brian R Davidson; Emmanuel Tsochatzis; Kurinchi Selvan Gurusamy
Journal:  Cochrane Database Syst Rev       Date:  2021-04-10

8.  Direct costs of care in a randomized controlled trial of endoscopic sclerotherapy versus emergency portacaval shunt for bleeding esophageal varices in cirrhosis--Part 4.

Authors:  Marshall J Orloff; Jon I Isenberg; Henry O Wheeler; Kevin S Haynes; Horacio Jinich-Brook; Roderick Rapier; Florin Vaida; Robert J Hye
Journal:  J Gastrointest Surg       Date:  2010-09-08       Impact factor: 3.452

9.  Secondary prevention of variceal bleeding in adults with previous oesophageal variceal bleeding due to decompensated liver cirrhosis: a network meta-analysis.

Authors:  Maria Corina Plaz Torres; Lawrence Mj Best; Suzanne C Freeman; Danielle Roberts; Nicola J Cooper; Alex J Sutton; Davide Roccarina; Amine Benmassaoud; Laura Iogna Prat; Norman R Williams; Mario Csenar; Dominic Fritche; Tanjia Begum; Sivapatham Arunan; Maxine Tapp; Elisabeth Jane Milne; Chavdar S Pavlov; Brian R Davidson; Emmanuel Tsochatzis; Kurinchi Selvan Gurusamy
Journal:  Cochrane Database Syst Rev       Date:  2021-03-30

10.  Transjugular intrahepatic portosystemic shunt versus surgical shunting in the management of portal hypertension.

Authors:  Long Huang; Qing-Sheng Yu; Qi Zhang; Ju-Da Liu; Zhen Wang
Journal:  Chin Med J (Engl)       Date:  2015-03-20       Impact factor: 2.628

  10 in total

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