M Yamamoto1, G Egusa, H Hara, M Yamakido. 1. Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
Abstract
OBJECTIVE: To investigate the association of visceral fat accumulation and carotid atherosclerosis in non-obese men with normal glucose tolerance. SUBJECTS: Ninety eight middle-aged men with normal glucose tolerance who had a body mass index (BMI) < 25 kg/m2 (mean age: 52.6 y, mean BMI: 22.5 kg/m2). METHOD: Using ultrasonography, we simultaneously measured the abdominal fat distribution and intima-media thickness (IMT) of the carotid artery wall. RESULTS: Pmax, an index of the absolute amount of visceral fat, was found to be significantly correlated with IMT and fasting Insulin concentration (r = 0.37, P < 0.005 and r = 0.54, P < 0.0001). Abdominal wall fat index (AFI), the ratio of maximum thickness of the preperitioneal fat and the minimum thickness of the subcutaneous fat, was not correlated with IMT. CONCLUSION: Visceral fat accumulation may play a role in the progression of atherosclerosis even in non-obese middle-aged men.
OBJECTIVE: To investigate the association of visceral fat accumulation and carotid atherosclerosis in non-obesemen with normal glucose tolerance. SUBJECTS: Ninety eight middle-aged men with normal glucose tolerance who had a body mass index (BMI) < 25 kg/m2 (mean age: 52.6 y, mean BMI: 22.5 kg/m2). METHOD: Using ultrasonography, we simultaneously measured the abdominal fat distribution and intima-media thickness (IMT) of the carotid artery wall. RESULTS: Pmax, an index of the absolute amount of visceral fat, was found to be significantly correlated with IMT and fasting Insulin concentration (r = 0.37, P < 0.005 and r = 0.54, P < 0.0001). Abdominal wall fat index (AFI), the ratio of maximum thickness of the preperitioneal fat and the minimum thickness of the subcutaneous fat, was not correlated with IMT. CONCLUSION: Visceral fat accumulation may play a role in the progression of atherosclerosis even in non-obese middle-aged men.
Authors: Alexandra Cremona; Kevin Hayes; Clodagh S O'Gorman; Ciara Ní Laighin; Khadijah I Ismail; Alan E Donnelly; Jill Hamilton; Amanda Cotter Journal: BMC Med Imaging Date: 2019-12-17 Impact factor: 1.930
Authors: Susanne Holzhauer; Renate M L Zwijsen; Vincent W V Jaddoe; Guenther Boehm; Henriette A Moll; Paul G Mulder; Veronica A Kleyburg-Linkers; Albert Hofman; Jacqueline C M Witteman Journal: Eur J Epidemiol Date: 2009-07-29 Impact factor: 8.082