Literature DB >> 934571

Acidosis, local anesthetics, and the newborn.

W U Brown, G C Bell, M H Alper.   

Abstract

Four newborn infants were studied following maternal epidural block with lidocaine or mepivacaine. Each of these neonates, born with a pH of 7.23 or below in the umbilical vein blood, showed an elevated fetal-to-maternal concentration ratio, a possible manifestation of ion trapping of a weak base.

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Year:  1976        PMID: 934571

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  12 in total

Review 1.  Treatment of cardiac arrhythmias during pregnancy: safety considerations.

Authors:  J A Joglar; R L Page
Journal:  Drug Saf       Date:  1999-01       Impact factor: 5.606

Review 2.  Adverse effects and drug interactions associated with local and regional anaesthesia.

Authors:  M Naguib; M M Magboul; A H Samarkandi; M Attia
Journal:  Drug Saf       Date:  1998-04       Impact factor: 5.606

Review 3.  Maternal cardiac arrhythmias during pregnancy and lactation.

Authors:  Rachael Cordina; Mark A McGuire
Journal:  Obstet Med       Date:  2010-03-04

Review 4.  Clinical pharmacokinetics of local anaesthetics.

Authors:  G T Tucker; L E Mather
Journal:  Clin Pharmacokinet       Date:  1979 Jul-Aug       Impact factor: 6.447

Review 5.  Drug kinetics in childbirth.

Authors:  R L Nation
Journal:  Clin Pharmacokinet       Date:  1980 Jul-Aug       Impact factor: 6.447

Review 6.  Risk-benefit assessment of anaesthetic agents in the puerperium.

Authors:  J Kanto
Journal:  Drug Saf       Date:  1991 Jul-Aug       Impact factor: 5.606

Review 7.  Rare procedures during delivery room resuscitation--cardioversion of ventricular tachycardia in an asphyctic neonate.

Authors:  K M Heinonen
Journal:  Intensive Care Med       Date:  1992       Impact factor: 17.440

Review 8.  The pharmacokinetics of antiarrhythmic agents in pregnancy and lactation.

Authors:  G M Mitani; I Steinberg; E J Lien; E C Harrison; U Elkayam
Journal:  Clin Pharmacokinet       Date:  1987-04       Impact factor: 6.447

9.  Disposition of the adrenergic blocker metoprolol and its metabolite OH-metoprolol in maternal plasma, amniotic fluid and capillary blood of the neonate.

Authors:  S Lindeberg; P Lundborg; C G Regårdh; B Sandström
Journal:  Eur J Clin Pharmacol       Date:  1987       Impact factor: 2.953

Review 10.  Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal-Fetal Drug Transfer.

Authors:  André Dallmann; Xiaomei I Liu; Gilbert J Burckart; John van den Anker
Journal:  J Clin Pharmacol       Date:  2019-09       Impact factor: 3.126

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