| Literature DB >> 9339450 |
T Iwasawa1, H Matoba, A Ogi, H Kurihara, K Saito, T Yoshida, S Matsubara, A Nozaki.
Abstract
The apparent diffusion coefficient (ADC) in the optic nerve was measured from diffusion-weighted magnetic resonance imaging using an intravoxel incoherent motion (IVIM) sequence. The subjects were seven normal volunteers and eight patients with multiple sclerosis (MS) with a total of four optic nerves with acute neuritis and nine nerves with chronic neuritis. The mean ADC (4.18 +/- 1.13 x 10(-3) mm2/s, n = 9) in the optic nerves with chronic neuritis was significantly higher than that in normal volunteers (1.56 +/- 0.675 x 10(-3) mm2/s, n = 14) and that in the nerves with acute neuritis (0.94 +/- 0.43 x 10(-3) mm2/s n = 4) (P < 0.001). The ADC is useful in assessing MS foci in the optic nerves.Entities:
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Year: 1997 PMID： 9339450 DOI： 10.1002/mrm.1910380317
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668