Literature DB >> 9338020

Maintenance pharmacological immunosuppressive strategies in renal transplantation.

J P Vella1, M H Sayegh.   

Abstract

Current maintenance immunosuppressive regimens for transplantation are based on three classes of drugs: corticosteroids, immunophilin-binding agents (eg, cyclosporin and tacrolimus), and antimetabolites (eg, azathioprine and mycophenolate). Drugs from the various classes inhibit the immune system at different points and are thus synergistic when used in combination.

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Year:  1997        PMID: 9338020      PMCID: PMC2431407          DOI: 10.1136/pgmj.73.861.386

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  24 in total

1.  Cancers complicating organ transplantation.

Authors:  I Penn
Journal:  N Engl J Med       Date:  1990-12-20       Impact factor: 91.245

Review 2.  Cyclosporine.

Authors:  B D Kahan
Journal:  N Engl J Med       Date:  1989-12-21       Impact factor: 91.245

3.  Long-term complications of renal transplantation.

Authors:  W E Braun
Journal:  Kidney Int       Date:  1990-05       Impact factor: 10.612

Review 4.  Novel immunotherapeutic strategies using MHC derived peptides.

Authors:  M H Sayegh; A M Krensky
Journal:  Kidney Int Suppl       Date:  1996-01       Impact factor: 10.545

5.  Oral versus intravenous high-dose steroid treatment of renal allograft rejection. The big shot or not?

Authors:  D Gray; H Shepherd; A Daar; D O Oliver; P J Morris
Journal:  Lancet       Date:  1978-01-21       Impact factor: 79.321

6.  Cutaneous malignant neoplasms in patients with renal transplants.

Authors:  A K Gupta; C J Cardella; H F Haberman
Journal:  Arch Dermatol       Date:  1986-11

7.  Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases.

Authors:  J Chung; C J Kuo; G R Crabtree; J Blenis
Journal:  Cell       Date:  1992-06-26       Impact factor: 41.582

8.  Tapering or discontinuing cyclosporine for financial reasons--a single-center experience.

Authors:  C E Sanders; J J Curtis; B A Julian; R S Gaston; P A Jones; D A Laskow; M H Deierhoi; W H Barber; A G Diethelm
Journal:  Am J Kidney Dis       Date:  1993-01       Impact factor: 8.860

9.  Causes of graft loss beyond two years in the cyclosporine era.

Authors:  J Dunn; D Golden; C T Van Buren; R M Lewis; J Lawen; B D Kahan
Journal:  Transplantation       Date:  1990-02       Impact factor: 4.939

10.  RS-61443 (mycophenolate mofetil). A multicenter study for refractory kidney transplant rejection.

Authors:  H W Sollinger; F O Belzer; M H Deierhoi; A G Diethelm; T A Gonwa; R S Kauffman; G B Klintmalm; S V McDiarmid; J Roberts; J T Rosenthal
Journal:  Ann Surg       Date:  1992-10       Impact factor: 12.969

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