Literature DB >> 9333594

[Value of K+ and Mg2+ in treatment of acute myocardial infarct].

M Kunert1, L Scheuble, H Stolzenburg, H Gülker.   

Abstract

A critical role analysis of literature concerning the effects of intravenous magnesium on arrhythmias and mortality in acute myocardial infarction shows discrepant results and often inappropriate methods. So far neither an antiarrhythmic efficacy nor prophylactic effects with respect to mortality could be demonstrated. In contrast, potassium substitution should be performed in the setting of acute myocardial infarction with documented hypokalemia (K+ < 3.5 mmol/l) because of increased risk of ventricular arrhythmias. According to the documented results of the trials reviewed in this article no recommendations for the routine use of magnesium in myocardial infarction can be given.

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Year:  1997        PMID: 9333594     DOI: 10.1007/bf03042657

Source DB:  PubMed          Journal:  Herz        ISSN: 0340-9937            Impact factor:   1.443


  22 in total

1.  Arrhythmias following experimental coronary occlusion and their response to drugs.

Authors:  B B CLARK; J R CUMMINGS
Journal:  Ann N Y Acad Sci       Date:  1956-11-16       Impact factor: 5.691

2.  Hypokalemia from beta 2-receptor stimulation by circulating epinephrine.

Authors:  M J Brown
Journal:  Am J Cardiol       Date:  1985-08-30       Impact factor: 2.778

3.  Intravenous magnesium in acute myocardial infarction.

Authors:  H S Rasmussen; P McNair; P Norregard; V Backer; O Lindeneg; S Balslev
Journal:  Lancet       Date:  1986-02-01       Impact factor: 79.321

4.  Serum potassium concentration as a risk factor of ventricular arrhythmias early in acute myocardial infarction.

Authors:  J E Nordrehaug; K A Johannessen; G von der Lippe
Journal:  Circulation       Date:  1985-04       Impact factor: 29.690

5.  Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)

Authors:  K L Woods; S Fletcher; C Roffe; Y Haider
Journal:  Lancet       Date:  1992-06-27       Impact factor: 79.321

6.  Efficacy of intravenous magnesium in acute myocardial infarction in reducing arrhythmias and mortality. Meta-analysis of magnesium in acute myocardial infarction.

Authors:  S M Horner
Journal:  Circulation       Date:  1992-09       Impact factor: 29.690

7.  Magnesium in the prevention of lethal arrhythmias in acute myocardial infarction.

Authors:  A S Abraham; D Rosenmann; M Kramer; J Balkin; M M Zion; H Farbstien; U Eylath
Journal:  Arch Intern Med       Date:  1987-04

8.  Magnesium therapy in acute myocardial infarction when patients are not candidates for thrombolytic therapy.

Authors:  M Shechter; H Hod; P Chouraqui; E Kaplinsky; B Rabinowitz
Journal:  Am J Cardiol       Date:  1995-02-15       Impact factor: 2.778

9.  Serum magnesium and potassium in acute myocardial infarction. Influence on ventricular arrhythmias.

Authors:  H Kafka; L Langevin; P W Armstrong
Journal:  Arch Intern Med       Date:  1987-03

10.  Prevention of ventricular fibrillation with magnesium sulfate.

Authors:  G E Billman; R S Hoskins
Journal:  Eur J Pharmacol       Date:  1988-12-06       Impact factor: 4.432

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