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Literature DB >> 9330872

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

Abstract

Cadherins play important roles in cell-cell adhesion during tissue differentiation. Cadherins are linked to the actin cytoskeleton by catenins (beta-catenin/armadillo, plakoglobin, and alpha-catenin). Recent results show that beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases and phosphatases and Wnt/Wingless. Interplay between these cytoskeletal complexes and signaling pathways may regulate morphogenesis.

Entities: Disease Gene

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Year: 1997 PMID： 9330872 DOI： 10.1016/s0955-0674(97)80122-6

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

106 in total

Review 1. Patterning of cell assemblies regulated by adhesion receptors of the cadherin superfamily.

Authors: M Takeichi; S Nakagawa; S Aono; T Usui; T Uemura
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2000-07-29 Impact factor: 6.237

2. Differential sensitivity of human epithelial cells to Pseudomonas aeruginosa exoenzyme S.

Authors: E M McGuffie; J E Fraylick; D J Hazen-Martin; T S Vincent; J C Olson
Journal: Infect Immun Date: 1999-07 Impact factor: 3.441

3. Genetic dissection of cadherin function during nephrogenesis.

Authors: Ulf Dahl; Anders Sjödin; Lionel Larue; Glenn L Radice; Stefan Cajander; Masatoshi Takeichi; Rolf Kemler; Henrik Semb
Journal: Mol Cell Biol Date: 2002-03 Impact factor: 4.272

4. Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.

Authors: Yoshinari Tanaka; Hiroyuki Nakanishi; Shigeki Kakunaga; Noriko Okabe; Tomomi Kawakatsu; Kazuya Shimizu; Yoshimi Takai
Journal: Mol Biol Cell Date: 2003-04 Impact factor: 4.138

5. gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.

Authors: F T Kolligs; B Kolligs; K M Hajra; G Hu; M Tani; K R Cho; E R Fearon
Journal: Genes Dev Date: 2000-06-01 Impact factor: 11.361

6. T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin.

Authors: A I Barth; D B Stewart; W J Nelson
Journal: Proc Natl Acad Sci U S A Date: 1999-04-27 Impact factor: 11.205

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

Review 1. Patterning of cell assemblies regulated by adhesion receptors of the cadherin superfamily.

2. Differential sensitivity of human epithelial cells to Pseudomonas aeruginosa exoenzyme S.

3. Genetic dissection of cadherin function during nephrogenesis.

4. Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.

5. gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.

6. T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin.

7. Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.

8. Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection.

9. Primate embryonic stem cells create their own niche while differentiating in three-dimensional culture systems.

10. Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin.