| Literature DB >> 9330716 |
R L Rasmusson1, S Wang, R C Castellino, M J Morales, H C Strauss.
Abstract
A recently discovered class of ancillary subunits has been shown to modify the inactivation properties of alpha-subunits belonging to the Kv1 family of potassium channels. One of these subunits, Kv beta 1.2, modifies intrinsic alpha-subunit C-type inactivation. N-type inactivation and open channel block have been proposed to increase the rate of development of C-type inactivation. We demonstrate here that Kv beta 1.2 has kinetic properties which are consistent with rapid open channel block.Mesh:
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Year: 1997 PMID: 9330716 DOI: 10.1007/978-1-4615-5959-7_3
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622