Literature DB >> 932963

Isolation of 10, 11-epoxide of protriptyline in rat urine after protriptyline administration.

V Rovei, G Belvedere, C Pantarotto, A Frigerio.   

Abstract

The 10, 11-epoxide, 10-hydroxy, and 10, 11-dihydrodiol metabolites of protriptyline were identified in rat urine collected after the administration of 40 mg/kg ip of protriptyline. Mass spectrometric characterization confirmed the structure of these metabolites.

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Year:  1976        PMID: 932963     DOI: 10.1002/jps.2600650605

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Metabolism of amineptine in rat, dog and man.

Authors:  L Grislain; P Gelé; N Bromet; W Luijten; J P Volland; E Mocaer; A Kamoun
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1990 Oct-Dec       Impact factor: 2.441

  1 in total

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