Literature DB >> 9328782

Hypokalemia leading to torsades de pointes. Munchausen's disorder or bulimia nervosa?

L E Krahn1, J Lee, J W Richardson, M J Martin, M K O'Connor.   

Abstract

A 45-year-old woman traveled over 1000 miles from a major metropolitan area to obtain another opinion for medically refractory diarrhea. She had an extremely complicated medical history with no outside records or family members accompanying her to give collateral history. She had multiple previous diagnostic evaluations including 13 surgical procedures and many therapeutic trials of various medications. She acknowledged a preoccupation with weight and appearance, described previous attempts to diet, and repetitively denied purging, including laxative abuse. During her hospitalization she had two episodes of torsades de pointes requiring cardiac defibrillation. Laboratory testing revealed hypokalemia at the time of these events, and a toxicology screen was positive for bisacodyl, confirming laxative abuse. When confronted by a combined team of cardiology, gastroenterology, and psychiatry specialist, she admitted her laxative abuse and surrendered her supply of Dulcolax tablets. The discussion addresses the procedures employed to detect her surreptitious medication use, the near lethal cardiac complications, and the appropriate psychiatric diagnosis.

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Year:  1997        PMID: 9328782     DOI: 10.1016/s0163-8343(97)00057-1

Source DB:  PubMed          Journal:  Gen Hosp Psychiatry        ISSN: 0163-8343            Impact factor:   3.238


  4 in total

Review 1.  The medical complications associated with purging.

Authors:  K Jean Forney; Jennifer M Buchman-Schmitt; Pamela K Keel; Guido K W Frank
Journal:  Int J Eat Disord       Date:  2016-02-15       Impact factor: 4.861

Review 2.  Laxative abuse: epidemiology, diagnosis and management.

Authors:  James L Roerig; Kristine J Steffen; James E Mitchell; Christie Zunker
Journal:  Drugs       Date:  2010-08-20       Impact factor: 9.546

3.  Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes.

Authors:  Kyriacos Mouyis; Darlington Okonko; Constantinos G Missouris
Journal:  Case Rep Cardiol       Date:  2016-05-23

4.  Hypokalemia in patients with anorexia nervosa during refeeding is associated with binge-purge behavior, lower body mass index, and hypoalbuminemia.

Authors:  Michitaka Funayama; Yu Mimura; Taketo Takata; Akihiro Koreki; Satoyuki Ogino; Shin Kurose; Yusuke Shimizu
Journal:  J Eat Disord       Date:  2021-08-06
  4 in total

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