Literature DB >> 9326179

Pulsed high-dose dexamethasone in chronic autoimmune haemolytic anaemia of warm type.

O Meyer1, D Stahl, P Beckhove, D Huhn, A Salama.   

Abstract

The management of patients with autoimmune haemolytic anaemia of warm type (AIHA) is often problematic. Recently, pulsed high-dose dexamethasone (HDD) has been shown to be effective in the treatment of autoimmune thrombocytopenic purpura (AITP). In this study we treated seven patients with AIHA with HDD. The regimen recommended for treatment of refractory AITP (40 mg dexamethasone for 4 d at the beginning of each 28 d cycle) was employed in almost all cases. Prior to dexamethasone administration, haemolysis was decompensated in all seven patients. HDD was well tolerated and led to an improvement of haemolysis in all cases.

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Year:  1997        PMID: 9326179     DOI: 10.1046/j.1365-2141.1997.3203137.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  3 in total

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Review 2.  Treatment of autoimmune hemolytic anemias.

Authors:  Alberto Zanella; Wilma Barcellini
Journal:  Haematologica       Date:  2014-10       Impact factor: 9.941

Review 3.  Treatment Options for Primary Autoimmune Hemolytic Anemia: A Short Comprehensive Review.

Authors:  Abdulgabar Salama
Journal:  Transfus Med Hemother       Date:  2015-08-10       Impact factor: 3.747

  3 in total

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