C C Chan1, I W Rodger. Show Affiliations » 1. Department of Pharmacology, Merck Frosst Centre for Therapeutic Research Kirkland, Quebec, Canada.
Abstract
Entities: Gene
Mesh: See more » AnimalsAnti-Inflammatory Agents, Non-Steroidal/pharmacologyAnti-Inflammatory Agents, Non-Steroidal/therapeutic useAnti-Inflammatory Agents, Non-Steroidal/toxicityBone Neoplasms/enzymologyBone Neoplasms/pathologyCyclooxygenase 1Cyclooxygenase 2Cyclooxygenase 2 InhibitorsCyclooxygenase Inhibitors/pharmacologyCyclooxygenase Inhibitors/therapeutic useCyclooxygenase Inhibitors/toxicityDinoprostone/biosynthesisDrug Evaluation, PreclinicalHumansIndans/pharmacologyIndans/toxicityIndomethacin/pharmacologyIndomethacin/toxicityInflammation/drug therapyInflammation/metabolismIsoenzymes/antagonists & inhibitorsIsoenzymes/bloodIsoenzymes/drug effectsIsoenzymes/physiologyMembrane ProteinsNeoplasm Proteins/antagonists & inhibitorsOsteosarcoma/enzymologyOsteosarcoma/pathologyProstaglandin-Endoperoxide Synthases/bloodProstaglandin-Endoperoxide Synthases/drug effectsProstaglandin-Endoperoxide Synthases/physiologyRatsSaimiriStomach Ulcer/chemically inducedSubstrate Specificity
Substances: See more » Anti-Inflammatory Agents, Non-SteroidalCyclooxygenase 2 InhibitorsCyclooxygenase InhibitorsIndansIsoenzymesL 745337Membrane ProteinsNeoplasm ProteinsCyclooxygenase 1Cyclooxygenase 2PTGS1 protein, humanPTGS2 protein, humanProstaglandin-Endoperoxide SynthasesPtgs1 protein, ratDinoprostoneIndomethacin
Year: 1997 PMID: 9321947 DOI: 10.1007/978-1-4899-1813-0_24
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622