| Literature DB >> 932142 |
Abstract
A method for the quantitative determination of sulphinpyrazone in plasma and urine is described. The drug is extracted from the acidified aqueous phase with 1-chlorobutane-ethylene dichloride (4:1) and separated from its metabolites by high-performance liquid chromatography on 5-mum LiChrosorb using dichloromethane-ethanol-water-acetic acid (79.1:19:1.9:0.002) as the mobile phase. The sensitivity limit is 0,2mug/ml using a 1-ml sample. Examples of applications are given.Entities:
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Year: 1976 PMID： 932142 DOI： 10.1016/s0021-9673(00)85018-9
Source DB: PubMed Journal: J Chromatogr