| Literature DB >> 9317046 |
P A Denoel1, R M Crawford, M S Zygmunt, A Tibor, V E Weynants, F Godfroid, D L Hoover, J J Letesson.
Abstract
A bacterioferritin (BFR) deletion mutant of Brucella melitensis 16M was generated by gene replacement. The deletion was complemented with a broad-host-range vector carrying the wild-type bfr gene, pBBR-bfr. The survival and growth of the mutant, B. melitensis PAD 2-78, were similar to those of its parental strain in human monocyte-derived macrophages (MDM). These results suggest that BFR is not essential for the intracellular survival of B. melitensis in human MDM.Entities:
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Year: 1997 PMID: 9317046 PMCID: PMC175622 DOI: 10.1128/iai.65.10.4337-4340.1997
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441