Literature DB >> 9317046

Survival of a bacterioferritin deletion mutant of Brucella melitensis 16M in human monocyte-derived macrophages.

P A Denoel1, R M Crawford, M S Zygmunt, A Tibor, V E Weynants, F Godfroid, D L Hoover, J J Letesson.   

Abstract

A bacterioferritin (BFR) deletion mutant of Brucella melitensis 16M was generated by gene replacement. The deletion was complemented with a broad-host-range vector carrying the wild-type bfr gene, pBBR-bfr. The survival and growth of the mutant, B. melitensis PAD 2-78, were similar to those of its parental strain in human monocyte-derived macrophages (MDM). These results suggest that BFR is not essential for the intracellular survival of B. melitensis in human MDM.

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Year:  1997        PMID: 9317046      PMCID: PMC175622          DOI: 10.1128/iai.65.10.4337-4340.1997

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  26 in total

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Review 3.  Bacterioferritin: a hemoprotein member of the ferritin family.

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4.  Mapping and identification of Brucella melitensis proteins by two-dimensional electrophoresis and microsequencing.

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5.  Deletion of purE attenuates Brucella melitensis 16M for growth in human monocyte-derived macrophages.

Authors:  E S Drazek; H S Houng; R M Crawford; T L Hadfield; D L Hoover; R L Warren
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

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10.  Complete sequence of the gene encoding the bacterioferritin subunit of Mycobacterium avium subspecies silvaticum.

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Journal:  Gene       Date:  1994-12-02       Impact factor: 3.688

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  6 in total

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Authors:  A P Teixeira-Gomes; A Cloeckaert; M S Zygmunt
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3.  Effect of P39 gene deletion in live Brucella vaccine strains on residual virulence and protective activity in mice.

Authors:  A Tibor; I Jacques; L Guilloteau; J M Verger; M Grayon; V Wansard; J J Letesson
Journal:  Infect Immun       Date:  1998-11       Impact factor: 3.441

4.  Identification of the perosamine synthetase gene of Brucella melitensis 16M and involvement of lipopolysaccharide O side chain in Brucella survival in mice and in macrophages.

Authors:  F Godfroid; B Taminiau; I Danese; P Denoel; A Tibor; V Weynants; A Cloeckaert; J Godfroid; J J Letesson
Journal:  Infect Immun       Date:  1998-11       Impact factor: 3.441

5.  Comparative proteome analysis of Brucella melitensis vaccine strain Rev 1 and a virulent strain, 16M.

Authors:  Michel Eschenbrenner; Mary Ann Wagner; Troy A Horn; Jo Ann Kraycer; Cesar V Mujer; Sue Hagius; Philip Elzer; Vito G DelVecchio
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6.  Ferritin mutants of Escherichia coli are iron deficient and growth impaired, and fur mutants are iron deficient.

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  6 in total

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