Literature DB >> 9316225

DBT: a partial D phenotype associated with the low-incidence antigen Rh32.

M Wallace1, C Lomas-Francis, E Beckers, M Bruce, G Campbell, S Chatfield, N Nagao, Y Okubo, A Opalka, M Overbeeke, M Scott, D Voak.   

Abstract

Eight probands are described with a D phenotype in which a partial D antigen is associated with Rh32 antigen; three of these probands were investigated because of the anti-D in their serum. The partial D lacks epD1-epD5 and epD9 and some epD6/7 and only expresses epD8 and other parts of epD6/7. The strength of the partial D antigen varies between unrelated DBT individuals. The Rh32 antigen of the DBT cells is weaker than that of D(C)(e) cells. Tests on DBT, DFR and R0Har cells with anti-epD6/7 split these monoclonal anti-D into eight patterns of reaction. A new pattern of reactions was observed, presaging a new epitope, but this was not numbered.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9316225     DOI: 10.1046/j.1365-3148.1997.d01-32.x

Source DB:  PubMed          Journal:  Transfus Med        ISSN: 0958-7578            Impact factor:   2.019


  2 in total

1.  Anti-D in a D-positive patient: autoantibody or alloantibody?

Authors:  Stefania Vaglio; Maria Paola Perrone; Maria Cristina Arista; Luca Laurenti; Gabriella Girelli
Journal:  Blood Transfus       Date:  2007-01       Impact factor: 3.443

2.  RHD Genotyping of Rh-Negative and Weak D Phenotype among Blood Donors in Southeast Iran.

Authors:  Younes Sadeghi-Bojd; Naser Amirizadeh; Arezoo Oodi
Journal:  Int J Hematol Oncol Stem Cell Res       Date:  2021-10-01
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.