Literature DB >> 9315942

MDMA induced hyperthermia: a survivor with an initial body temperature of 42.9 degrees C.

A Mallick1, A R Bodenham.   

Abstract

A young male survived hyperpyrexia (42.9 degrees C) following MDMA ("Ecstasy") ingestion. He developed convulsions, rhabdomyolysis, metabolic acidosis, and respiratory failure. This was successfully managed by assisted ventilation, aggressive fluid therapy, and the early administration of dantrolene, in addition to cooling measures. This is the first report of a survivor with such a severe hyperpyrexia.

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Year:  1997        PMID: 9315942      PMCID: PMC1343106          DOI: 10.1136/emj.14.5.336

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN: 1351-0622


  7 in total

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Authors:  A R Bodenham; A Mallick
Journal:  Intensive Care Med       Date:  1996-07       Impact factor: 17.440

2.  Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat.

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Review 3.  Heatstroke: a new look at an ancient disease.

Authors:  A Bouchama
Journal:  Intensive Care Med       Date:  1995-08       Impact factor: 17.440

Review 4.  Hazards associated with the recreational drug 'ecstasy'.

Authors:  B O'Connor
Journal:  Br J Hosp Med       Date:  1994 Nov 16-Dec 13

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Authors:  M J Cuomo; P G Dyment; V M Gammino
Journal:  J Am Coll Health       Date:  1994-05

Review 6.  Hyperthermia associated with 3,4-methylenedioxyethamphetamine ('Eve').

Authors:  B Tehan; R Hardern; A Bodenham
Journal:  Anaesthesia       Date:  1993-06       Impact factor: 6.955

7.  Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

Authors:  J A Henry; K J Jeffreys; S Dawling
Journal:  Lancet       Date:  1992-08-15       Impact factor: 79.321

  7 in total
  12 in total

1.  Effects of (+/-)3,4-methylenedioxymethamphetamine, (+/-)3,4-methylenedioxyamphetamine and methamphetamine on temperature and activity in rhesus macaques.

Authors:  R D Crean; S A Davis; S N Von Huben; C C Lay; S N Katner; M A Taffe
Journal:  Neuroscience       Date:  2006-07-28       Impact factor: 3.590

2.  Influences of activity wheel access on the body temperature response to MDMA and methamphetamine.

Authors:  N W Gilpin; M J Wright; G Dickinson; S A Vandewater; J U Price; M A Taffe
Journal:  Pharmacol Biochem Behav       Date:  2011-05-13       Impact factor: 3.533

3.  Hyperthermia induced by 3,4-methylenedioxymethamphetamine in unrestrained rhesus monkeys.

Authors:  Michael A Taffe; Christopher C Lay; Stefani N Von Huben; Sophia A Davis; Rebecca D Crean; Simon N Katner
Journal:  Drug Alcohol Depend       Date:  2005-11-11       Impact factor: 4.492

4.  The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.

Authors:  Annis O Mechan; Blanca Esteban; Esther O'Shea; J Martin Elliott; M Isabel Colado; A Richard Green
Journal:  Br J Pharmacol       Date:  2002-01       Impact factor: 8.739

5.  Increased anxiety and "depressive" symptoms months after MDMA ("ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes.

Authors:  Iain S McGregor; Clint G Gurtman; Kirsten C Morley; Kelly J Clemens; Arjan Blokland; Kong M Li; Jennifer L Cornish; Glenn E Hunt
Journal:  Psychopharmacology (Berl)       Date:  2003-04-17       Impact factor: 4.530

6.  Thermoregulatory effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans.

Authors:  Robert R Freedman; Chris-Ellyn Johanson; Manuel E Tancer
Journal:  Psychopharmacology (Berl)       Date:  2005-11-09       Impact factor: 4.530

7.  Oral administration of (+/-)3,4-methylenedioxymethamphetamine and (+)methamphetamine alters temperature and activity in rhesus macaques.

Authors:  Rebecca D Crean; Sophia A Davis; Michael A Taffe
Journal:  Pharmacol Biochem Behav       Date:  2007-04-03       Impact factor: 3.533

Review 8.  Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview.

Authors:  João Paulo Capela; Helena Carmo; Fernando Remião; Maria Lourdes Bastos; Andreas Meisel; Félix Carvalho
Journal:  Mol Neurobiol       Date:  2009-04-17       Impact factor: 5.590

9.  Attenuation of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-induced rhabdomyolysis with alpha1- plus beta3-adrenoreceptor antagonists.

Authors:  Jon E Sprague; Robert E Brutcher; Edward M Mills; David Caden; Daniel E Rusyniak
Journal:  Br J Pharmacol       Date:  2004-05-24       Impact factor: 8.739

Review 10.  Clinical review: Major consequences of illicit drug consumption.

Authors:  Robert J Devlin; John A Henry
Journal:  Crit Care       Date:  2008-01-08       Impact factor: 9.097

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