Literature DB >> 9315241

Lipid peroxidation and antioxidant enzymes in erythrocytes and tissues in aged diabetic rats.

P Yadav1, S Sarkar, D Bhatnagar.   

Abstract

Antidiabetic treatment with powdered fruit of Capparis decidua decreased alloxan induced lipid peroxidation (LPO) significantly in erythrocytes, kidney and heart. Erythrocyte superoxide dismutase (SOD) activity decreased while the kidney and heart SOD increased in diabetic animals. These alterations in SOD were counteracted by insulin as well as with powdered fruit of C. decidua. Increased catalase (CAT) activity in erythrocytes, liver, kidney and heart with C. decidua treatment indicate that the treatment may neutralize H2O2 toxicity by its increased decomposition by CAT. Result shows that treatment with C. decidua lowers alloxan induced LPO and alters SOD and CAT enzymes to reduce oxidative stress.

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Year:  1997        PMID： 9315241

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN： 0019-5189            Impact factor:   0.818


  10 in total

Review 1.  Prevention of non-enzymatic glycosylation (glycation): Implication in the treatment of diabetic complication.

Authors:  H Younus; S Anwar
Journal:  Int J Health Sci (Qassim)       Date:  2016-04

2.  Evaluation of antioxidant properties of berries.

Authors:  P Rani; K Meena Unni; J Karthikeyan
Journal:  Indian J Clin Biochem       Date:  2004-07

3.  Oxidative stress and gene expression of antioxidant enzymes in the renal cortex of streptozotocin-induced diabetic rats.

Authors:  Pallavi V Limaye; Nandula Raghuram; S Sivakami
Journal:  Mol Cell Biochem       Date:  2003-01       Impact factor: 3.396

4.  Sedative and anticonvulsant effects of an alcoholic extract of Capparis decidua.

Authors:  Manoj Goyal; B P Nagori; D Sasmal
Journal:  J Nat Med       Date:  2009-05-19       Impact factor: 2.343

5.  Hyperlipidemia, increased lipid peroxidation and changes in antioxidant enzymes, Na(+)-K(+)-ATPase in erythrocytes of type 2 diabetic patients in andhra pradesh.

Authors:  R Giri; M M Kesavulu; B K Rao; V Ramana; C A Rao
Journal:  Indian J Clin Biochem       Date:  1999-07

6.  A pharmacological appraisal of medicinal plants with antidiabetic potential.

Authors:  Vasim Khan; Abul Kalam Najmi; Mohd Akhtar; Mohd Aqil; Mohd Mujeeb; K K Pillai
Journal:  J Pharm Bioallied Sci       Date:  2012-01

7.  Indian herbs and herbal drugs used for the treatment of diabetes.

Authors:  Manisha Modak; Priyanjali Dixit; Jayant Londhe; Saroj Ghaskadbi; Thomas Paul A Devasagayam
Journal:  J Clin Biochem Nutr       Date:  2007-05       Impact factor: 3.114

8.  Kolaviron improved resistance to oxidative stress and inflammation in the blood (erythrocyte, serum, and plasma) of streptozotocin-induced diabetic rats.

Authors:  Omolola R Ayepola; Nicole L Brooks; Oluwafemi O Oguntibeju
Journal:  ScientificWorldJournal       Date:  2014-03-24

9.  Curcumin regulates gene expression of insulin like growth factor, B-cell CLL/lymphoma 2 and antioxidant enzymes in streptozotocin induced diabetic rats.

Authors:  Sabry M El-Bahr
Journal:  BMC Complement Altern Med       Date:  2013-12-24       Impact factor: 3.659

Review 10.  Lipid peroxidation: pathophysiological and pharmacological implications in the eye.

Authors:  Ya Fatou Njie-Mbye; Madhura Kulkarni-Chitnis; Catherine A Opere; Aaron Barrett; Sunny E Ohia
Journal:  Front Physiol       Date:  2013-12-16       Impact factor: 4.566
  10 in total

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