| Literature DB >> 9315239 |
Abstract
Ocimum sanctum fixed oil and linolenic acid were found to possess significant antiinflammatory activity against PGE2, leukotriene and arachidonic acid-induced paw edema. Plant lipids like linseed oil and soyabean oil containing linolenic acid when tested along with O. sanctum fixed oil, also showed significant inhibition of carrageenan-induced paw edema. The results suggest that linolenic acid present in O. sanctum fixed oil has the capacity to block both the cyclooxygenase and lipoxygenase pathways of arachidonate metabolism and could be responsible for the antiinflammatory activity of the oil.Entities:
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Year: 1997 PMID： 9315239
Source DB: PubMed Journal: Indian J Exp Biol ISSN： 0019-5189 Impact factor: 0.818