Literature DB >> 9315107

The role of natural killer cells in viral infections.

D M See1, P Khemka, L Sahl, T Bui, J G Tilles.   

Abstract

Natural killer (NK) cells are important effectors for the lysis of both neoplastic and virus-infected cells. Lectin-like receptors on human NK cells, such as NKR-PIA and CD94, bind to target cell carbohydrate ligands and initiate the lytic process. In addition, P58 and P70 bind to major histocompatibility class I antigens on targets and mediate negative signals. Models using NK cell-deficient mice have proven useful in elaborating the role of NK cells in the immune defence against multiple viral agents. In addition, studies in humans have suggested a vital role of NK cells in the host defence against human immunodeficiency virus, herpesviruses, hepatitis B and C and other viruses. Several genetic disorders, chronic illnesses and infections have been associated with decreased NK function.

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Year:  1997        PMID: 9315107     DOI: 10.1046/j.1365-3083.1997.d01-121.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN: 0300-9475            Impact factor:   3.487


  12 in total

1.  Evaluation of natural killer cell activity.

Authors:  J H Cox; M deSouza
Journal:  Mol Biotechnol       Date:  2000-06       Impact factor: 2.695

2.  Perforin and Fas/Fas ligand-mediated cytotoxicity in acute and chronic woodchuck viral hepatitis.

Authors:  P D Hodgson; M D Grant; T I Michalak
Journal:  Clin Exp Immunol       Date:  1999-10       Impact factor: 4.330

3.  Functional analyses of natural killer cells in macaques infected with neurovirulent simian immunodeficiency virus.

Authors:  T M Shieh; D L Carter; R L Blosser; J L Mankowski; M C Zink; J E Clements
Journal:  J Neurovirol       Date:  2001-02       Impact factor: 2.643

4.  Selective down-regulation of the NKG2D ligand H60 by mouse cytomegalovirus m155 glycoprotein.

Authors:  Milena Hasan; Astrid Krmpotic; Zsolt Ruzsics; Ivan Bubic; Tihana Lenac; Anne Halenius; Andrea Loewendorf; Martin Messerle; Hartmut Hengel; Stipan Jonjic; Ulrich H Koszinowski
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

5.  Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells.

Authors:  Valentina Voigt; Catherine A Forbes; Joanne N Tonkin; Mariapia A Degli-Esposti; Hamish R C Smith; Wayne M Yokoyama; Anthony A Scalzo
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-03       Impact factor: 11.205

6.  The in vitro immunomodulatory effects of glyconutrients on peripheral blood mononuclear cells of patients with chronic fatigue syndrome.

Authors:  D M See; P Cimoch; S Chou; J Chang; J Tilles
Journal:  Integr Physiol Behav Sci       Date:  1998 Jul-Sep

7.  IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection.

Authors:  Maria A Stacey; Morgan Marsden; Eddie C Y Wang; Gavin W G Wilkinson; Ian R Humphreys
Journal:  J Immunol       Date:  2011-08-17       Impact factor: 5.422

Review 8.  Bracing NK cell based therapy to relegate pulmonary inflammation in COVID-19.

Authors:  Madhan Jeyaraman; Sathish Muthu; Asawari Bapat; Rashmi Jain; E S Sushmitha; Arun Gulati; Talagavadi Channaiah Anudeep; Shirodkar Jaswandi Dilip; Niraj Kumar Jha; Dhruv Kumar; Kavindra Kumar Kesari; Shreesh Ojha; Sunny Dholpuria; Gaurav Gupta; Harish Dureja; Dinesh Kumar Chellappan; Sachin Kumar Singh; Kamal Dua; Saurabh Kumar Jha
Journal:  Heliyon       Date:  2021-07-21

Review 9.  T cell memory in the context of persistent herpes viral infections.

Authors:  Nicole Torti; Annette Oxenius
Journal:  Viruses       Date:  2012-07-20       Impact factor: 5.048

10.  Clinical relevance of natural killer cells following hematopoietic stem cell transplantation.

Authors:  Jeanne M Palmer; Kamalakannan Rajasekaran; Monica S Thakar; Subramaniam Malarkannan
Journal:  J Cancer       Date:  2012-12-05       Impact factor: 4.207

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