Literature DB >> 9315029

Smoking during pregnancy measured by population cotinine testing.

D M Tappin1, R P Ford, P J Schluter.   

Abstract

AIM: To establish a baseline cross-sectional prevalence of maternal smoking, measured by antenatal serum cotinine testing, in a population of pregnant women.
METHODS: Residual sera from first and second routine antenatal blood samples were collected anonymously over a six-month period for pregnancies within the Canterbury region. Cotinine levels were measured by an ELISA test with a result of > 14 ng/mL indicative of active smoking. Only pregnancies ending in a confirmed live birth were considered in smoking prevalence calculations. There was a total of 1948 eligible residual blood samples.
RESULTS: Of the 414 residual blood samples available for the first two months of pregnancy, 146 (35.3%) were found to be positive for cotinine. Smoking prevalence decreased over pregnancy so that by the third trimester 225 (26.8%) of 838 samples were cotinine positive. Infants born from smoking mothers had significantly lower birth weights.
CONCLUSIONS: In 1994, a third of women tested in early pregnancy and a quarter of women tested in late pregnancy were identified as being smokers. Repeated objective cross-sectional surveys will allow accurate assessment of the efficacy of smokefree interventions both before and during pregnancy.

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Year:  1997        PMID: 9315029

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  3 in total

1.  Is the hair nicotine level a more accurate biomarker of environmental tobacco smoke exposure than urine cotinine?

Authors:  W K Al-Delaimy; J Crane; A Woodward
Journal:  J Epidemiol Community Health       Date:  2002-01       Impact factor: 3.710

2.  Socio-demographic factors associated with smoking and smoking cessation among 426,344 pregnant women in New South Wales, Australia.

Authors:  Mohammed Mohsin; Adrian E Bauman
Journal:  BMC Public Health       Date:  2005-12-21       Impact factor: 3.295

3.  The Interplay between Maternal Smoking and Genes in Offspring Birth Weight.

Authors:  Rita Dias Pereira; Cornelius A Rietveld; Hans van Kippersluis
Journal:  medRxiv       Date:  2020-11-03
  3 in total

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