R Sachdev1, E Kemmann, M K Bohrer, I el-Danasouri. 1. Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School, New Brunswick 08901, USA.
Abstract
OBJECTIVE: To study the effects of human hydrosalpinx fluid on mouse embryo blastulation rate. DESIGN: Comparison of mouse embryo blastulation rate in media containing increasing concentrations of hydrosalpinx fluid. SETTING: Tertiary care center. PATIENT(S): Women undergoing laparoscopic evaluation or treatment for infertility noted to have hydrosalpinx or paratubal cyst. INTERVENTION(S): Exposure of mouse embryos to hydrosalpinx or paratubal cyst fluid collected during laparoscopy. MAIN OUTCOME MEASURE(S): Blastulation rate of mouse embryos. RESULT(S): Culture of mouse embryos at 0% (controls), 0.3%, 0.6%, and 0.9% hydrosalpinx fluid concentrations demonstrated significantly lower blastulation rate at each level compared with the controls. CONCLUSION(S): Hydrosalpinx fluid is highly embryotoxic.
OBJECTIVE: To study the effects of human hydrosalpinx fluid on mouse embryo blastulation rate. DESIGN: Comparison of mouse embryo blastulation rate in media containing increasing concentrations of hydrosalpinx fluid. SETTING: Tertiary care center. PATIENT(S): Women undergoing laparoscopic evaluation or treatment for infertility noted to have hydrosalpinx or paratubal cyst. INTERVENTION(S): Exposure of mouse embryos to hydrosalpinx or paratubal cyst fluid collected during laparoscopy. MAIN OUTCOME MEASURE(S): Blastulation rate of mouse embryos. RESULT(S): Culture of mouse embryos at 0% (controls), 0.3%, 0.6%, and 0.9% hydrosalpinx fluid concentrations demonstrated significantly lower blastulation rate at each level compared with the controls. CONCLUSION(S): Hydrosalpinx fluid is highly embryotoxic.
Authors: L I Barmat; E Rauch; S Spandorfer; A Kowalik; E S Sills; G Schattman; H C Liu; Z Rosenwaks Journal: J Assist Reprod Genet Date: 1999-08 Impact factor: 3.412
Authors: Mohamed A Bedaiwy; Tommaso Falcone; Jeffrey M Goldberg; Marjan Attaran; Rakesh Sharma; Kurt Miller; David R Nelson; Ashok Agarwal Journal: J Assist Reprod Genet Date: 2005-04 Impact factor: 3.412