| Literature DB >> 931467 |
R D Sofia, B N Dixit, H Barry.
Abstract
The level of serotonin (5-HT) was increased in the whole rat brain as well as in the hypothalamus plus midbrain region at 0.5 hr after the fifth or sixth daily dose of delta9-tetrahydrocannabinol (THC), 20.0 mg/kg, i.p., respectively. A decreased rate of 5-HT synthesis was also observed. A slight development of tolerance was indicated by the fact that elevation of 5-HT was smaller than that seen after a single dose (1).Entities:
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Year: 1977 PMID： 931467
Source DB: PubMed Journal: Arch Int Pharmacodyn Ther ISSN： 0003-9780