Changes in the frequency of electroencephalographic rhythms of the rat caused by single, intraperitoneal injections of ethanol.

Ethanol (2-4 g/kg, i.p.) caused a slowing of the three main forms of electroencephalographic activity of the waking rat (hippocampal theta rhythm, and hippocampal and neocortical large-irregular amplitude activity). The effect was dose-dependent within those dose ranges, and bore a gross relation to blood ethanol levels. Lower dosages (0.5-1 g/kg) had no effect.