Literature DB >> 9314

Gastric mucus effusion elicited by oral copper compounds: potential anti-ulcer activity.

K D Rainsford, M W Whitehouse.   

Abstract

In rats, both Cu(I) and Cu(II) show an irritancy profile not shared with Cu degrees or Zn(II) or Ni(II). The gastric response to Cu(II), i.e. copius fluid and mucus secretion, can protect the stomach from the acute ulcerative effects of aspirin or physical stress administered subsequently.

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Year:  1976        PMID: 9314     DOI: 10.1007/BF01927608

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  5 in total

Review 1.  The biochemical pathology of aspirin-induced gastric damage.

Authors:  K D Rainsford
Journal:  Agents Actions       Date:  1975-10

2.  SPECIFIC STAINING OF SULPHATE GROUPS WITH ALCIAN BLUE AT LOW PH.

Authors:  R LEV; S S SPICER
Journal:  J Histochem Cytochem       Date:  1964-04       Impact factor: 2.479

3.  Copper chelates as possible active forms of the antiarthritic agents.

Authors:  J R Sorenson
Journal:  J Med Chem       Date:  1976-01       Impact factor: 7.446

4.  Computer calculation of equilibrium concentrations in mixtures of metal ions and complexing species.

Authors:  D D Perrin; I G Sayce
Journal:  Talanta       Date:  1967-07       Impact factor: 6.057

5.  Electronmicroscopic observations on the effects of orally administered aspirin and aspirin-bicarbonate mixtures on the development of gastric mucosal damage in the rat.

Authors:  K D Rainsford
Journal:  Gut       Date:  1975-07       Impact factor: 23.059

  5 in total
  7 in total

Review 1.  Drug-induced gastrointestinal disease.

Authors:  M G Bramble; C O Record
Journal:  Drugs       Date:  1978-06       Impact factor: 9.546

2.  Anti-inflammatory properties of copper implants in the rat paw edema: a preliminary study.

Authors:  H H Dollwet; S P Schmidt; R E Seeman
Journal:  Agents Actions       Date:  1981-12

3.  A comparison of the anti-inflammatory effects of copper aspirinate and other copper salts in the rat and guinea pig.

Authors:  A J Lewis
Journal:  Agents Actions       Date:  1978-04

4.  The comparative gastric ulcerogenic activities of non-steroid anti-inflammatory drugs.

Authors:  K D Rainsford
Journal:  Agents Actions       Date:  1977-12

5.  The protective effects of sulphasalazine against ethanol-induced gastric damage in rats.

Authors:  C H Cho; C W Ogle; E L Sevilla
Journal:  Br J Pharmacol       Date:  1987-09       Impact factor: 8.739

6.  Copper and inflammation.

Authors:  M W Whitehouse; W R Walker
Journal:  Agents Actions       Date:  1978-01

7.  Anti-inflammatory activity of a dermally applied copper salicylate preparation (Alcusal).

Authors:  W R Walker; S J Beveridge; M W Whitehouse
Journal:  Agents Actions       Date:  1980-04
  7 in total

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