Literature DB >> 9311924

Addiction is a brain disease, and it matters.

A I Leshner1.   

Abstract

Scientific advances over the past 20 years have shown that drug addiction is a chronic, relapsing disease that results from the prolonged effects of drugs on the brain. As with many other brain diseases, addiction has embedded behavioral and social-context aspects that are important parts of the disorder itself. Therefore, the most effective treatment approaches will include biological, behavioral, and social-context components. Recognizing addiction as a chronic, relapsing brain disorder characterized by compulsive drug seeking and use can impact society's overall health and social policy strategies and help diminish the health and social costs associated with drug abuse and addiction.

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Year:  1997        PMID: 9311924     DOI: 10.1126/science.278.5335.45

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  287 in total

1.  Substance abuse at the turn of the millennium.

Authors:  P R Kendall; J Hoey
Journal:  CMAJ       Date:  1999-05-18       Impact factor: 8.262

2.  Pathways to long-term recovery: a preliminary investigation.

Authors:  Alexandre B Laudet; Robert Savage; Daneyal Mahmood
Journal:  J Psychoactive Drugs       Date:  2002 Jul-Sep

3.  Neurofeedback Effects on Evoked and Induced EEG Gamma Band Reactivity to Drug-related Cues in Cocaine Addiction.

Authors:  Timothy Horrell; Ayman El-Baz; Joshua Baruth; Allan Tasman; Guela Sokhadze; Christopher Stewart; Estate Sokhadze
Journal:  J Neurother       Date:  2010-07

Review 4.  The addicted human brain: insights from imaging studies.

Authors:  Nora D Volkow; Joanna S Fowler; Gene-Jack Wang
Journal:  J Clin Invest       Date:  2003-05       Impact factor: 14.808

5.  An experimental evaluation of recovery management checkups (RMC) for people with chronic substance use disorders.

Authors:  Michael Dennis; Christy K Scott; Rod Funk
Journal:  Eval Program Plann       Date:  2003-08

Review 6.  A Patient-Tailored Evidence-Based Approach for Developing Early Neuropsychological Training Programs in Addiction Settings.

Authors:  Benjamin Rolland; Fabien D'Hondt; Solène Montègue; Mélanie Brion; Eric Peyron; Julia D'Aviau de Ternay; Philippe de Timary; Mikaïl Nourredine; Pierre Maurage
Journal:  Neuropsychol Rev       Date:  2019-01-03       Impact factor: 7.444

7.  Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine.

Authors:  Ling-Yan Su; Rongcan Luo; Qianjin Liu; Jing-Ran Su; Lu-Xiu Yang; Yu-Qiang Ding; Lin Xu; Yong-Gang Yao
Journal:  Autophagy       Date:  2017-07-19       Impact factor: 16.016

Review 8.  Recent development in studies of tetrahydroprotoberberines: mechanism in antinociception and drug addiction.

Authors:  Hongyuan Chu; Guozhang Jin; Eitan Friedman; Xuechu Zhen
Journal:  Cell Mol Neurobiol       Date:  2007-08-21       Impact factor: 5.046

9.  Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence.

Authors:  Daijun Ling; Tianhua Niu; Yan Feng; Houxun Xing; Xiping Xu
Journal:  J Hum Genet       Date:  2003-12-18       Impact factor: 3.172

Review 10.  Symbiotic relationship of pharmacogenetics and drugs of abuse.

Authors:  Joni L Rutter
Journal:  AAPS J       Date:  2006-03-24       Impact factor: 4.009

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