Literature DB >> 930905

Surgical vagotomy and stomach wall ATP and ADP in pylorus--ligated rats.

G Mózsik, F Vizi.   

Abstract

The stomach wall ATP and ADP have been studied in rats, with and without bilateral surgical vagotomy, 24 hr after pylorus ligation. It was observed that the amounts and concentrations of ATP significantly decreased in both parts (corpus + antrum and forestomach) in pylorus-ligated rats, while the amounts and concentrations remained at a significantly higher level in pylorus-ligated + vagotomized rats. Changes in amounts and concentrations of ADP paralleled those of ATP. It has been concluded that a significant decrease of cellular ATP is necessary to produce gastric hypersecretion in ulceration in pylorus-ligated rats. This significant decrease of cellular ATP, in corpus + antrum and forestomach, can be prevented by bilateral surgical vagotomy.

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Year:  1977        PMID： 930905     DOI： 10.1007/bf01072860

Source DB:  PubMed          Journal:  Am J Dig Dis        ISSN： 0002-9211


  5 in total

1.  A biochemical-cellular-morphological explanation for antiulcerogenic effects of parasympatholytics and of surgical vagotomy in Shay rats.

Authors:  G Mózsik; B Kiss; M Krausz; T Jávor
Journal:  Scand J Gastroenterol       Date:  1969       Impact factor: 2.423

2.  Alterations in stomach wall ATP-ADP induced by atropine treatment.

Authors:  G Mózsik; T Jávor; E Daróczy
Journal:  Pharmacology       Date:  1970       Impact factor: 2.547

3.  Base alterations of nucleic acids in stomach wall after prolonged atropine treatment.

Authors:  G Mózsik; M Hauck; I Kóródy; Z Szepesi
Journal:  Eur J Pharmacol       Date:  1969-07       Impact factor: 4.432

4.  Some effects of prolonged treatment with atropine on the stomach wall of the rat (a biochemical-pharmacological approach of the effects of vagal exclusion--vagotomy and atropine treatment--on cellular-molecular level).

Authors:  G Mózsik; B Kiss; T Jávor; M Krausz
Journal:  Eur J Pharmacol       Date:  1969-07       Impact factor: 4.432

5.  Examination of stomach wall Mg2+-Na+-K+-dependent ATPase, ATP, and ADP in pylorus-ligated rats.

Authors:  G Mózsik; F Vizi
Journal:  Am J Dig Dis       Date:  1976-08
  5 in total
  4 in total

Review 1.  A biochemical and pharmacological approach to the genesis of ulcer disease. I. A model study of ethanol-induced injury to gastric mucosa in rats.

Authors:  G Mózsik; T Jávor
Journal:  Dig Dis Sci       Date:  1988-01       Impact factor: 3.199

2.  Impaired gastric mucosal energy metabolism in congestive gastropathy in cirrhotic patients.

Authors:  S Kawano; H Tanimura; S Tsuji; Y Takei; K Nagano; T Kashiwagi; H Fusamoto; T Kamada
Journal:  J Gastroenterol       Date:  1994-06       Impact factor: 7.527

3.  Examination of stomach wall Mg2+-Na+-K+-dependent ATPase, ATP, and ADP in pylorus-ligated rats.

Authors:  G Mózsik; F Vizi
Journal:  Am J Dig Dis       Date:  1976-08

Review 4.  Cellular Energetical Actions of "Chemical" and "Surgical" Vagotomy in Gastrointestinal Mucosal Damage and Protection: Similarities, Differences and Significance for Brain-Gut Function.

Authors:  Imre L Szabo; Jozsef Czimmer; Gyula Mozsik
Journal:  Curr Neuropharmacol       Date:  2016       Impact factor: 7.363
  4 in total

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