Literature DB >> 9307948

Dose to the contralateral breast: a comparison of two techniques using the enhanced dynamic wedge versus a standard wedge.

W B Warlick1, J H O'Rear, L Earley, J H Moeller, D K Gaffney, D D Leavitt.   

Abstract

The dose to the contralateral breast has been associated with an increased risk of developing a second breast malignancy. Varying techniques have been devised and described in the literature to minimize this dose. Metal beam modifiers such as standard wedges are used to improve the dose distribution in the treated breast, but unfortunately introduce an increased scatter dose outside the treatment field, in particular to the contralateral breast. The enhanced dynamic wedge is a means of remote wedging created by independently moving one collimator jaw through the treatment field during dose delivery. This study is an analysis of differing doses to the contralateral breast using two common clinical set-up techniques with the enhanced dynamic wedge versus the standard metal wedge. A tissue equivalent block (solid water), modeled to represent a typical breast outline, was designed as an insert in a Rando phantom to simulate a standard patient being treated for breast conservation. Tissue equivalent material was then used to complete the natural contour of the breast and to reproduce appropriate build-up and internal scatter. Thermoluminescent dosimeter (TLD) rods were placed at predetermined distances from the geometric beam's edge to measure the dose to the contralateral breast. A total of 35 locations were used with five TLDs in each location to verify the accuracy of the measured dose. The radiation techniques used were an isocentric set-up with co-planar, non divergent posterior borders and an isocentric set-up with a half beam block technique utilizing the asymmetric collimator jaw. Each technique used compensating wedges to optimize the dose distribution. A comparison of the dose to the contralateral breast was then made with the enhanced dynamic wedge vs. the standard metal wedge. The measurements revealed a significant reduction in the contralateral breast dose with the enhanced dynamic wedge compared to the standard metal wedge in both set-up techniques. The dose was measured at varying distances from the geometric field edge, ranging from 2 to 8 cm. The average dose with the enhanced dynamic wedge was 2.7-2.8%. The average dose with the standard wedge was 4.0-4.7%. Thermoluminescent dosimeter measurements suggest an increase in both scattered electrons and photons with metal wedges. The enhanced dynamic wedge is a practical clinical advance which improves the dose distribution in patients undergoing breast conservation while at the same time minimizing dose to the contralateral breast, thereby reducing the potential carcinogenic effects.

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Year:  1997        PMID: 9307948     DOI: 10.1016/s0958-3947(97)00015-0

Source DB:  PubMed          Journal:  Med Dosim        ISSN: 1873-4022            Impact factor:   1.482


  8 in total

1.  Dosimetric comparison of the field-in-field technique and tangential wedged beams for breast irradiation.

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Journal:  Jpn J Radiol       Date:  2011-12-21       Impact factor: 2.374

2.  Dosimetric comparison of field in field intensity-modulated radiotherapy technique with conformal radiotherapy techniques in breast cancer.

Authors:  Tülay Ercan; Sefik Iğdem; Gül Alço; Funda Zengin; Selin Atilla; Maktav Dinçer; Sait Okkan
Journal:  Jpn J Radiol       Date:  2010-05-29       Impact factor: 2.374

3.  Hybrid volumetric modulated arc therapy for hypofractionated radiotherapy of breast cancer: a treatment planning study.

Authors:  Alexander Venjakob; Michael Oertel; Dominik Alexander Hering; Christos Moustakis; Uwe Haverkamp; Hans Theodor Eich
Journal:  Strahlenther Onkol       Date:  2020-10-17       Impact factor: 3.621

4.  Dosimetric Comparison of Treatment Plans Using Physical Wedge and Enhanced Dynamic Wedge for the Planning of Breast Radiotherapy.

Authors:  Zhenia Gopalakrishnan; Raghuram K Nair; P Raghukumar; B Sarin
Journal:  J Med Phys       Date:  2018 Jan-Mar

5.  Enhanced dynamic wedge output factors for Varian 2300CD and the case for a reference database.

Authors:  Christopher F Njeh
Journal:  J Appl Clin Med Phys       Date:  2015-09-08       Impact factor: 2.102

6.  The impact of adjuvant therapy on contralateral breast cancer risk and the prognostic significance of contralateral breast cancer: a population based study in the Netherlands.

Authors:  Michael Schaapveld; Otto Visser; W J Louwman; Pax H B Willemse; Elisabeth G E de Vries; Winette T A van der Graaf; Renée Otter; Jan Willem W Coebergh; Flora E van Leeuwen
Journal:  Breast Cancer Res Treat       Date:  2007-08-09       Impact factor: 4.872

7.  Improvement of dose distribution with irregular surface compensator in whole breast radiotherapy.

Authors:  Fujita Hideki; Kuwahata Nao; Hattori Hiroyuki; Kinoshita Hiroshi; Fukuda Haruyuki
Journal:  J Med Phys       Date:  2013-07

8.  Dosimetric Comparison of Irregular Surface Compensator and Field-in-Field for Whole Breast Radiotherapy.

Authors:  Nao Kuwahata; Hideki Fujita; Hideaki Yamanishi; Eiichiro Okazaki; Haruyuki Fukuda
Journal:  J Med Phys       Date:  2018 Apr-Jun
  8 in total

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