| Literature DB >> 9307216 |
Y Ebisawa1, F Miyaji, T Kokubo, K Ohura, T Nakamura.
Abstract
Bioactive and ferrimagnetic glass-ceramics are useful as thermoseeds for hyperthermia treatment of cancer. A heat treatment of a 40(FeO, Fe2O3)-60CaO x SiO2 wt% glass gives a ferrimagnetic glass-ceramic containing 36 wt% magnetite in a CaO x SiO2 matrix. However, it does not show bioactivity since a small amount of iron ion remains in the matrix. In the present study, bioactivities of ferrimagnetic glass-ceramics which were prepared by heat treatment of glasses of the composition 40(FeO, Fe2O3)-60CaO x SiO2 (wt%) with various components added at 100:3 weight ratio were evaluated in vitro by examining bone-like apatite formation on their surfaces in a simulated body fluid. It was found that glass-ceramics with Na2O or B2O3 added in combination with P2O5 show bioactivity.Entities:
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Year: 1997 PMID： 9307216 DOI： 10.1016/s0142-9612(97)00067-7
Source DB: PubMed Journal: Biomaterials ISSN： 0142-9612 Impact factor: 12.479