D J Commins1, J M Chen. 1. Department of Otolaryngology, Sunnybrook Health Science Centre, University of Toronto, Canada.
Abstract
OBJECTIVE: This study aimed to heighten the awareness of multiple sclerosis (MS) as a cause of multiple acute cranial nerve palsies. DATA SOURCES: The authors report on a case with audiovestibular and facial nerve deficits as the manifesting symptoms of MS. A literature review of brain stem-presenting clinical features of MS was carried out using key words in a Medline search from 1969 through 1996. In addition, relevant articles from earlier reports were obtained. CONCLUSION: Brain stem involvement occurs as the presenting feature of MS in up to 15% of cases. Prompt diagnosis and early treatment may reduce morbidity of this common neurologic condition, and a high index of suspicion needs to be maintained to avoid misdiagnosis.
OBJECTIVE: This study aimed to heighten the awareness of multiple sclerosis (MS) as a cause of multiple acute cranial nerve palsies. DATA SOURCES: The authors report on a case with audiovestibular and facial nerve deficits as the manifesting symptoms of MS. A literature review of brain stem-presenting clinical features of MS was carried out using key words in a Medline search from 1969 through 1996. In addition, relevant articles from earlier reports were obtained. CONCLUSION: Brain stem involvement occurs as the presenting feature of MS in up to 15% of cases. Prompt diagnosis and early treatment may reduce morbidity of this common neurologic condition, and a high index of suspicion needs to be maintained to avoid misdiagnosis.
Authors: Francesca Yoshie Russo; Massimo Ralli; Daniele De Seta; Patrizia Mancini; Alessandro Lambiase; Marco Artico; Marco de Vincentiis; Antonio Greco Journal: Immunol Res Date: 2018-12 Impact factor: 2.829