| Literature DB >> 9302995 |
Y Wei, Y Zhang, U Derewenda, X Liu, W Minor, R K Nakamoto, A V Somlyo, A P Somlyo, Z S Derewenda.
Abstract
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.Entities:
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Year: 1997 PMID： 9302995 DOI： 10.1038/nsb0997-699
Source DB: PubMed Journal: Nat Struct Biol ISSN： 1072-8368