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Literature DB >> 9302219

Differences in humoral responses to the p24 antigen between Ethiopian and Swedish human immunodeficiency virus type 1-infected patients may suggest influences from a T-helper 2-like phenotype.

T Kebede¹, S Britton, T Fehniger, A Vahlne, M Sällberg.

Abstract

The levels of human immunodeficiency virus type 1 p24 antibodies and p24 antigen among 256 Ethiopians and Africans and 86 Swedes were compared. The elevated levels of total anti-p24 immunoglobulin G (IgG) and anti-p24 IgG4 among the Ethiopian and African patients suggest influences from T-helper-cell type 2-like responses.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1997 PMID： 9302219 PMCID： PMC170613 DOI： 10.1128/cdli.4.5.627-629.1997

Source DB: PubMed Journal: Clin Diagn Lab Immunol ISSN： 1071-412X

20 in total

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6. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

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Differences in humoral responses to the p24 antigen between Ethiopian and Swedish human immunodeficiency virus type 1-infected patients may suggest influences from a T-helper 2-like phenotype.

1. Resistance to Leishmania major in mice.

2. Sequential switching from mu to epsilon via gamma 4 in human B cells stimulated with IL-4 and hydrocortisone.

3. Immunochemical structure of the carboxy-terminal part of hepatitis B e antigen: identification of internal and surface-exposed sequences.

4. IgE and IgG subclass regulation by IL-4 and IFN-gamma in human helminth infections. Assessment by B cell precursor frequencies.

5. Human immunoglobulin class and IgG subclass regulation: dual action of interleukin-4.

6. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

7. Prevalence and persistence of antibody titers to recombinant HIV-1 core and matrix proteins in HIV-1 infection.

8. Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals.

9. Relationship between cell-free viraemia, antigenaemia and antibody levels in HIV-1-infected Ethiopian patients.

10. Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells.

1. Variability and immunogenicity of human immunodeficiency virus type 1 p24 gene quasispecies.