Literature DB >> 9300920

Quantitative analysis of C60 fullerene in blood and tissues by high-performance liquid chromatography with photodiode-array and mass spectrometric detection.

F Moussa1, M Pressac, E Genin, S Roux, F Trivin, A Rassat, R Céolin, H Szwarc.   

Abstract

A high-performance liquid chromatographic (HPLC) assay method for C60 fullerene, in blood, liver and spleen using photodiode-array detection or mass spectrometric detection (LC-MS) and C70 fullerene, as the internal standard, is described. The recovery from mouse blood and tissues spiked with micronized C60 exceeds 90%. The method is linear from 0.05 to 200 mg of C60 per liter of blood and from 0.05 to 5.00% of C60 per tissue weight. The limit of detection of the method is 0.1 ng of C60 per injection. This method was applied to mouse blood and tissue samples after intraperitoneal administration of a micronized C60 suspension.

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Year:  1997        PMID： 9300920     DOI： 10.1016/s0378-4347(97)00228-4

Source DB:  PubMed          Journal:  J Chromatogr B Biomed Sci Appl        ISSN： 1387-2273


  6 in total

Review 1.  Beyond nC60: strategies for identification of transformation products of fullerene oxidation in aquatic and biological samples.

Authors:  Benny F G Pycke; Tzu-Chiao Chao; Pierre Herckes; Paul Westerhoff; Rolf U Halden
Journal:  Anal Bioanal Chem       Date:  2012-05-28       Impact factor: 4.142

2.  Strategies for quantifying C(60) fullerenes in environmental and biological samples and implications for studies in environmental health and ecotoxicology.

Authors:  Benny F G Pycke; Troy M Benn; Pierre Herckes; Paul Westerhoff; Rolf U Halden
Journal:  Trends Analyt Chem       Date:  2011-01-01       Impact factor: 12.296

Review 3.  Quantitative analysis of fullerene nanomaterials in environmental systems: a critical review.

Authors:  Carl W Isaacson; Markus Kleber; Jennifer A Field
Journal:  Environ Sci Technol       Date:  2009-09-01       Impact factor: 9.028

4.  C60-fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects.

Authors:  Nicole Levi; Roy R Hantgan; Mark O Lively; David L Carroll; Gaddamanugu L Prasad
Journal:  J Nanobiotechnology       Date:  2006-12-14       Impact factor: 10.435

5.  Skeleton labeled 13C-carbon nanoparticles for the imaging and quantification in tumor drainage lymph nodes.

Authors:  Ping Xie; Qian Xin; Sheng-Tao Yang; Tiantian He; Yuanfang Huang; Guangfu Zeng; Maosheng Ran; Xiaohai Tang
Journal:  Int J Nanomedicine       Date:  2017-07-11

6.  [60]Fullerene for Medicinal Purposes, A Purity Criterion towards Regulatory Considerations.

Authors:  Sanaz Keykhosravi; Ivo B Rietveld; Diana Couto; Josep Lluis Tamarit; Maria Barrio; René Céolin; Fathi Moussa
Journal:  Materials (Basel)       Date:  2019-08-12       Impact factor: 3.623
  6 in total

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