The meiotic pairing behaviour in human spermatocytes carrier of chromosome anomalies and their repercussions on reproductive fitness. II. Robertsonian and reciprocal translocations. A European collaborative study.

The pairing behaviour of pachytene chromosomes was studied in men carrier of Robertsonian and reciprocal translocations, by analysis of synaptonemal complexes at the electron microscopy level. The human meiotic data were collected from European laboratories in order to test the current theories and to link the spermatogenic breakdown, and the pregnancy wastage to the mode of pairing and their consequences.