PURPOSE: To illustrate the spectrum of sarcoidosis involving the eye and brain and the difficulties of confirming its clinical diagnosis. METHODS: The presentation of two unusual case reports of patients with ocular and cerebral involvement with sarcoidosis. RESULTS: Tissue biopsy, an essential component in the differential diagnosis, was required to confirm the diagnosis of sarcoidosis in each patient. CONCLUSIONS: Sarcoidosis remains an enigmatic disease with protean manifestations and widely differing outcomes.
PURPOSE: To illustrate the spectrum of sarcoidosis involving the eye and brain and the difficulties of confirming its clinical diagnosis. METHODS: The presentation of two unusual case reports of patients with ocular and cerebral involvement with sarcoidosis. RESULTS: Tissue biopsy, an essential component in the differential diagnosis, was required to confirm the diagnosis of sarcoidosis in each patient. CONCLUSIONS:Sarcoidosis remains an enigmatic disease with protean manifestations and widely differing outcomes.