Literature DB >> 9296283

1,3-Dimethylpyrimidoheterocycles as antibacterial agents.

H H Zoorob1, M Abou Elzahab, M Abdel-Mogib, M A Ismail, M Abdel-Hamid.   

Abstract

1,3-Dimethylbarbituric acid was used as a versatile precursor for the preparation of annelated pyranopyrimidines 2 and 3a-c besides pyrrolopyrimidine 12. The isolated pyrazolopyrimidines 8a-c and 10 and fused pyrazolopyrimidines 14a-d were also synthesized. In addition the new obtained pyrimidoheterocycles were subjected to bacterial testings.

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Year:  1997        PMID: 9296283

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  2 in total

1.  Experimental and computational chemical studies on the corrosion inhibition of new pyrimidinone derivatives for copper in nitric acid.

Authors:  A S Fouda; M A Ismail; M A Khaled; A A El-Hossiany
Journal:  Sci Rep       Date:  2022-09-27       Impact factor: 4.996

2.  Three-component synthesis of pyrano[2,3-d]-pyrimidine dione derivatives facilitated by sulfonic acid nanoporous silica (SBA-Pr-SO3H) and their docking and urease inhibitory activity.

Authors:  Ghodsi Mohammadi Ziarani; Sakineh Faramarzi; Shima Asadi; Alireza Badiei; Roya Bazl; Massoud Amanlou
Journal:  Daru       Date:  2013-01-05       Impact factor: 3.117

  2 in total

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