Literature DB >> 9293159

Langerhans cells may trigger the psoriatic disease process via production of nitric oxide.

V B Morhenn1.   

Abstract

Psoriasis is a skin disease that appears to result from a dysfunction in the normal mechanism(s) that regulates wound healing. The Langerhans cell is a specialized epidermal macrophage that may instigate wound healing via production of nitric oxide and epidermal growth factor. Here, Vera Morhenn suggests that, whereas precise coordination of the synthesis of these two substances regulates normal wound healing, a disturbance of this regulation could lead to psoriasis.

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Year:  1997        PMID： 9293159     DOI： 10.1016/s0167-5699(97)01116-x

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  8 in total

1.  Expression profiles of elastase1 (NvElastaseI) and secretory leukocyte protease inhibitor (NvSLPI) during forelimb regeneration in adult Notophthalmus viridescens suggest a role in epithelial remodeling and delamination.

Authors:  Sandy Gian Vascotto; Shawn Beug; Richard A Liversage; Catherine Tsilfidis
Journal:  Dev Genes Evol       Date:  2006-03-01       Impact factor: 0.900

2.  Increased nitric oxide (NO) production by antigen-presenting dendritic cells is responsible for low allogeneic mixed leucocyte reaction (MLR) in primary biliary cirrhosis (PBC).

Authors:  K Yamamoto; S M Akbar; T Masumoto; M Onji
Journal:  Clin Exp Immunol       Date:  1998-10       Impact factor: 4.330

3.  Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.

Authors:  W L Trepicchio; M Ozawa; I B Walters; T Kikuchi; P Gilleaudeau; J L Bliss; U Schwertschlag; A J Dorner; J G Krueger
Journal:  J Clin Invest       Date:  1999-12       Impact factor: 14.808

Review 4.  What is a role of haeme oxygenase-1 in psoriasis? Current concepts of pathogenesis.

Authors:  Anna Wojas-Pelc; Janusz Marcinkiewicz
Journal:  Int J Exp Pathol       Date:  2007-04       Impact factor: 1.925

5.  Flk2+ myeloid progenitors are the main source of Langerhans cells.

Authors:  Ines Mende; Holger Karsunky; Irving L Weissman; Edgar G Engleman; Miriam Merad
Journal:  Blood       Date:  2005-11-01       Impact factor: 22.113

Review 6.  The Conundrum of Psoriatic Arthritis: a Pathogenetic and Clinical Pattern at the Midpoint of Autoinflammation and Autoimmunity.

Authors:  Rossana Scrivo; Salvatore D'Angelo; Antonio Carriero; Chiara Castellani; Fabio Massimo Perrotta; Fabrizio Conti; Matteo Vecellio; Carlo Selmi; Ennio Lubrano
Journal:  Clin Rev Allergy Immunol       Date:  2022-01-18       Impact factor: 8.667

Review 7.  Brain-skin connection: stress, inflammation and skin aging.

Authors:  Ying Chen; John Lyga
Journal:  Inflamm Allergy Drug Targets       Date:  2014

8.  Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-kappaB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line.

Authors:  Ana Luísa Vital; Margarida Gonçalo; M Teresa Cruz; Américo Figueiredo; Carlos B Duarte; M Celeste Lopes
Journal:  Mediators Inflamm       Date:  2003-04       Impact factor: 4.711
  8 in total

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