Literature DB >> 9293156

Glucocorticoids and immune function: unknown dimensions and new frontiers.

T Wilckens1, R De Rijk.   

Abstract

Despite the importance of glucocorticoids (GCs) to modern medicine, the physiological role of endogenous corticosteroids in immunomodulation is poorly understood. This article discusses evidence suggesting that endogenous GCs not only suppress but also direct and enhance immune functions. These often overlooked actions might well be more important than the inhibitory functions during host defence and the maintenance of homeostasis.

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Year:  1997        PMID： 9293156     DOI： 10.1016/s0167-5699(97)01111-0

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  47 in total

Review 1.  IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responses.

Authors:  G Haskó; C Szabó
Journal:  Br J Pharmacol       Date:  1999-07       Impact factor: 8.739

2.  Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice.

Authors:  Anatoly N Mikerov; Sanmei Hu; Faryal Durrani; Xiaozhuang Gan; Guirong Wang; Todd M Umstead; David S Phelps; Joanna Floros
Journal:  Microb Pathog       Date:  2012-01-20       Impact factor: 3.738

3.  Stress-induced enhancement of skin immune function: A role for gamma interferon.

Authors:  F S Dhabhar; A R Satoskar; H Bluethmann; J R David; B S McEwen
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

Review 4.  Enhancing versus suppressive effects of stress on immune function: implications for immunoprotection and immunopathology.

Authors:  Firdaus S Dhabhar
Journal:  Neuroimmunomodulation       Date:  2009-06-29       Impact factor: 2.492

5.  N-formyl-methionyl-leucyl-phenylalanine inhibits both gamma interferon- and interleukin-10-induced expression of FcgammaRI on human monocytes.

Authors:  M Beigier-Bompadre; P Barrionuevo; F Alves-Rosa; C J Rubel; M S Palermo; M A Isturiz
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

Review 6.  Glucocorticoids and central nervous system inflammation.

Authors:  Klaus Dinkel; William O Ogle; Robert M Sapolsky
Journal:  J Neurovirol       Date:  2002-12       Impact factor: 2.643

7.  Role of glucocorticoids and glucocorticoid receptor in priming of macrophages caused by glucocorticoid receptor blockade.

Authors:  Xiao-Yan Zhu; Yu-Jian Liu; Fei Diao; Jie Fan; Jian Lu; Ren-Bao Xu
Journal:  Endocrine       Date:  2007-04       Impact factor: 3.633

8.  Endogenous glucocorticoids control neutrophil mobilization from bone marrow to blood and tissues in non-inflammatory conditions.

Authors:  D M H Cavalcanti; C M C Lotufo; P Borelli; Z S Ferreira; R P Markus; S H P Farsky
Journal:  Br J Pharmacol       Date:  2007-11-05       Impact factor: 8.739

9.  Blockade of glucocorticoid receptors with RU486 attenuates cardiac damage and adipose tissue inflammation in a rat model of metabolic syndrome.

Authors:  Yuuri Takeshita; Shogo Watanabe; Takuya Hattori; Kai Nagasawa; Natsumi Matsuura; Keiji Takahashi; Toyoaki Murohara; Kohzo Nagata
Journal:  Hypertens Res       Date:  2015-07-09       Impact factor: 3.872

10.  Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production.

Authors:  Michael T Bailey; Sonja Kierstein; Satish Sharma; Matthew Spaits; Steven G Kinsey; Omar Tliba; Yassine Amrani; John F Sheridan; Reynold A Panettieri; Angela Haczku
Journal:  J Immunol       Date:  2009-06-15       Impact factor: 5.422
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