OBJECTIVE: To examine racial differences in disease expression in African American and Caucasian children with pauciarticular and polyarticular juvenile rheumatoid arthritis (JRA). METHODS: A retrospective chart review was conducted of 35 African American and 137 Caucasian children with pauciarticular and polyarticular JRA. RESULTS: African American children were significantly older than Caucasian children at the time of presentation. This was true both for the group as a whole and for each of the disease onset subtypes. African American children were less likely to have positive antinuclear antibody tests than Caucasian children. This finding paralleled a low incidence of uveitis in African American children. African American children were also more likely to have IgM rheumatoid factors (detected by latex agglutination) than Caucasian children. This was true even for African American children with pauciarticular JRA. CONCLUSION: There are significant phenotypic differences between African American and Caucasian children with JRA.
OBJECTIVE: To examine racial differences in disease expression in African American and Caucasian children with pauciarticular and polyarticular juvenile rheumatoid arthritis (JRA). METHODS: A retrospective chart review was conducted of 35 African American and 137 Caucasian children with pauciarticular and polyarticular JRA. RESULTS: African American children were significantly older than Caucasian children at the time of presentation. This was true both for the group as a whole and for each of the disease onset subtypes. African American children were less likely to have positive antinuclear antibody tests than Caucasian children. This finding paralleled a low incidence of uveitis in African American children. African American children were also more likely to have IgM rheumatoid factors (detected by latex agglutination) than Caucasian children. This was true even for African American children with pauciarticular JRA. CONCLUSION: There are significant phenotypic differences between African American and Caucasian children with JRA.
Authors: Christina F Pelajo; Sheila T Angeles-Han; Sampath Prahalad; Caitlin M Sgarlat; Trevor E Davis; Laurie C Miller; Jorge M Lopez-Benitez Journal: Rheumatol Int Date: 2013-05-10 Impact factor: 2.631
Authors: Lauren Fitzpatrick; K Alaine Broadaway; Lori Ponder; Sheila T Angeles-Han; Kirsten Jenkins; Kelly Rouster-Stevens; Christina F Pelajo; Karen Conneely; Michael P Epstein; Jorge Lopez-Benitez; Larry B Vogler; Sampath Prahalad Journal: J Rheumatol Date: 2016-02-15 Impact factor: 4.666
Authors: Christina F Pelajo; Jorge M Lopez-Benitez; David M Kent; Lori Lyn Price; Laurie C Miller; Bess Dawson-Hughes Journal: Rheumatol Int Date: 2011-12-25 Impact factor: 2.631
Authors: Petros E Carvounis; David C Herman; Stephen Cha; James P Burke Journal: Graefes Arch Clin Exp Ophthalmol Date: 2005-10-14 Impact factor: 3.117
Authors: Sheila T Angeles-Han; Courtney McCracken; Steven Yeh; Kirsten Jenkins; Daneka Stryker; Curtis Travers; Kelly Rouster-Stevens; Larry B Vogler; Scott R Lambert; Carolyn Drews-Botsch; Sampath Prahalad Journal: Am J Ophthalmol Date: 2015-08-06 Impact factor: 5.258
Authors: Petros E Carvounis; David C Herman; Stephen S Cha; James P Burke Journal: Graefes Arch Clin Exp Ophthalmol Date: 2004-09-17 Impact factor: 3.117