Literature DB >> 9292417

Effect of aqueous extract of Commiphora opobalsamum on blood pressure and heart rate in rats.

A S Abdul-Ghani1, R Amin.   

Abstract

The cardiovascular effects of aqueous extracts from the branches of Commiphora opobalsamum tree were investigated. The intravenous administration of 4 mg/kg of the aqueous extract depressed systemic arterial blood pressure by 20% (P < 0.01) and reduced heart rate of anaesthetised rats by 14% (P < 0.05). The hypotensive and the bradycardiac effects were immediate and in a dose related manner. The hypotensive effect of C. opobalsamum was inhibited by the pretreatment with atropine sulfate (1-4 mg/kg). These results suggest that the hypotensive effect of C. opobalsamum is due to the activation of muscarinic cholinergic receptors.

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Year:  1997        PMID： 9292417     DOI： 10.1016/s0378-8741(97)00063-9

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  5 in total

1.  Antibacterial Effects of Commiphora gileadensis Methanolic Extract on Wound Healing.

Authors:  Ayman Alhazmi; Abdullah F Aldairi; Ahmad Alghamdi; Anas Alomery; Abdulrahman Mujalli; Ahmad A Obaid; Wesam F Farrash; Mamdouh Allahyani; Ibrahim Halawani; Abdulelah Aljuaid; Sarah A Alharbi; Mazen Almehmadi; Moodi S Alharbi; Anmar A Khan; Maisam A Jastaniah; Abdulrhman Alghamdi
Journal:  Molecules       Date:  2022-05-21       Impact factor: 4.927

2.  Effect of Commiphora molmol on leukocytes proliferation in relation to histological alterations before and during healing from injury.

Authors:  Al-Said A Haffor
Journal:  Saudi J Biol Sci       Date:  2010-02-06       Impact factor: 4.219

3.  Species-specific molecular signature of Commiphora species of Saudi Arabia inferred from internal transcribed spacer sequences of nuclear ribosomal DNA.

Authors:  M Ajmal Ali
Journal:  Saudi J Biol Sci       Date:  2018-06-30       Impact factor: 4.219

4.  Bactericidal activity of Myrrh extracts and two dosage forms against standard bacterial strains and multidrug-resistant clinical isolates with GC/MS profiling.

Authors:  Noha Khalil; Sahar Fikry; Osama Salama
Journal:  AMB Express       Date:  2020-01-28       Impact factor: 3.298

5.  The Therapeutic Effect of Myrrh (Commiphora molmol) and Doxorubicin on Diethylnitrosamine Induced Hepatocarcinogenesis in Male Albino Rats.

Authors:  Hend Mohamed Anwar; Asmaa M Moghazy; Amany Abd Elhameid Osman; Amina A S Abdel Rahman
Journal:  Asian Pac J Cancer Prev       Date:  2021-07-01
  5 in total

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