Literature DB >> 9292274

Effect of long-term ingestion of chromium compounds on aggression, sex behavior and fertility in adult male rat.

H Bataineh1, M H al-Hamood, A Elbetieha, I Bani Hani.   

Abstract

The effects of long-term ingestion of chromium chloride (trivalent compound) and potassium dichromate (hexavalent compound) was investigated on sexual behavior, aggressive behavior and fertility in male rats. Adult male rats were exposed to chromium chloride and potassium dichromate in drinking water at a concentration of 1000 ppm for 12 weeks. The exposure of male rats to chromium chloride and potassium dichromate reduced the number of mounts. The exposure of male rats to potassium dichromate increased the time to ejaculation. On the other hand, the exposure of male rats to chromium chloride and potassium dichromate increased the post ejaculatory interval. The number of animals ejaculating were reduced in chromium chloride and potassium dichromate exposed male rats. The exposure of male rats to chromium chloride and potassium dichromate decreased lateralizations, boxing bouts and fights with stud male. The exposure of male rats to chromium chloride and potassium dichromate had no effect on fertility. Testes, seminal vesicle and preputial gland weights were significantly reduced in chromium chloride- and potassium dichromate-exposed males. In conclusion, the long-term ingestion of chromium chloride and potassium dichromate would have adverse effects on sexual behavior and territorial aggression in adult male rat.

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Year:  1997        PMID: 9292274     DOI: 10.3109/01480549709003875

Source DB:  PubMed          Journal:  Drug Chem Toxicol        ISSN: 0148-0545            Impact factor:   3.356


  12 in total

1.  Cytotoxicity and genotoxicity of hexavalent chromium in human and North Atlantic right whale (Eubalaena glacialis) lung cells.

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Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2009-07-24       Impact factor: 3.228

2.  Hexavalent chromium is cytotoxic and genotoxic to hawksbill sea turtle cells.

Authors:  Sandra S Wise; Hong Xie; Tomokazu Fukuda; W Douglas Thompson; John Pierce Wise
Journal:  Toxicol Appl Pharmacol       Date:  2014-06-19       Impact factor: 4.219

3.  A comparison of particulate hexavalent chromium cytotoxicity and genotoxicity in human and leatherback sea turtle lung cells from a one environmental health perspective.

Authors:  Rachel M Speer; Sandra S Wise; Tayler J Croom-Perez; AbouEl-Makarim Aboueissa; Mark Martin-Bras; Mike Barandiaran; Erick Bermúdez; John Pierce Wise
Journal:  Toxicol Appl Pharmacol       Date:  2019-05-18       Impact factor: 4.219

4.  The cytotoxicity and genotoxicity of hexavalent chromium in Steller sea lion lung fibroblasts compared to human lung fibroblasts.

Authors:  John Pierce Wise; Sandra S Wise; Amie L Holmes; Carolyne LaCerte; Fariba Shaffiey; AbouEl-Makarim Aboueissa
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2010-03-06       Impact factor: 3.228

5.  Short-term exposure of female rats to industrial metal salts: Effect on implantation and pregnancy.

Authors:  Hameed N Bataineh; Ziad M Bataineh; Haytham Daradka
Journal:  Reprod Med Biol       Date:  2007-08-06

6.  Relationship between cadmium content in semen and male infertility: a meta-analysis.

Authors:  Yiming Zhang; Shiping Li; Shu Li
Journal:  Environ Sci Pollut Res Int       Date:  2018-11-20       Impact factor: 4.223

7.  The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts.

Authors:  John Pierce Wise; Sandra S Wise; Carolyne LaCerte; John Pierce Wise; AbouEl-Makarim Aboueissa
Journal:  Environ Mol Mutagen       Date:  2011-01       Impact factor: 3.216

8.  The cytotoxicity and genotoxicity of particulate and soluble hexavalent chromium in leatherback sea turtle lung cells.

Authors:  Rachel M Speer; Catherine F Wise; Jamie L Young; AbouEl-Makarim Aboueissa; Mark Martin Bras; Mike Barandiaran; Erick Bermúdez; Lirio Márquez-D'Acunti; John Pierce Wise
Journal:  Aquat Toxicol       Date:  2018-03-04       Impact factor: 4.964

9.  Hexavalent chromium is cytotoxic and genotoxic to American alligator cells.

Authors:  Sandra S Wise; Catherine Wise; Hong Xie; Louis J Guillette; Cairong Zhu; John Pierce Wise; John Pierce Wise
Journal:  Aquat Toxicol       Date:  2015-12-12       Impact factor: 4.964

10.  Medaka (Oryzias latipes) as a sentinel species for aquatic animals: Medaka cells exhibit a similar genotoxic response as North Atlantic right whale cells.

Authors:  John Pierce Wise; Sandra S Wise; Britton C Goodale; Fariba Shaffiey; Scott Kraus; Ronald B Walter
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2008-10-05       Impact factor: 3.228

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