Literature DB >> 9290440

The etiology of fetal acidosis as determined by umbilical cord acid-base studies.

J W Johnson1, D S Richards.   

Abstract

OBJECTIVE: Our purpose was to determine whether umbilical cord acid-base values might be used to differentiate abruptio placentae from cord prolapse. STUDY
DESIGN: By use of a retrospective study design, umbilical cord blood acid-base values of 32 cases of severely acidotic acute abruptio placentae were statistically compared with those of 19 cases of severely acidotic acute cord prolapse with Fisher's exact test, Mann-Whitney U tests, and receiver-operator curve characteristic analyses.
RESULTS: No significant differences in electronic fetal heart rate record interpretations were detected. Highly significant differences in umbilical arterial and umbilical venous blood gas values were noted between the two groups. Most notable were the differences between umbilical venous and arterial blood gas values in the cord prolapse group. Receiver-operator characteristic curve analysis demonstrated that an umbilical venous-arterial pH difference of 0.15 was an effective cutoff value in differentiating cord prolapse from abruptio placentae (accuracy 92%).
CONCLUSION: Umbilical arterial blood gas values combined with umbilical venous blood gas values can assist in determining the pathogenesis of marked fetal acidosis.

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Year:  1997        PMID: 9290440     DOI: 10.1016/s0002-9378(97)70187-x

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  2 in total

Review 1.  Use of umbilical cord blood gas analysis in the assessment of the newborn.

Authors:  L Armstrong; B J Stenson
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2007-11       Impact factor: 5.747

Review 2.  Maternal and fetal Acid-base chemistry: a major determinant of perinatal outcome.

Authors:  L Omo-Aghoja
Journal:  Ann Med Health Sci Res       Date:  2014-01
  2 in total

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