| Literature DB >> 928954 |
J P Burke, M E Tumbleson, R N Seaman, A Y Sun.
Abstract
A biphasic effect of ethanol was observed on Ca2+-uptake activity, Ca2+-uncoupled respiratory control ratio (CURCR), and State 3 oxygen uptake. At low concentrations (0.1-0.5%) ethanol enhanced these activities, probably as the result of an increase in membrane fluidity. At higher levels (0.7-4.0%) ethanol had an inhibitory influence on mitochondrial activities as the membrane macromolecules were probably disturbed due to the hydrophobic alcohol-membrane interaction.Entities:
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Year: 1977 PMID： 928954
Source DB: PubMed Journal: Res Commun Chem Pathol Pharmacol ISSN： 0034-5164