Literature DB >> 9286302

Lymphocyte subsets in experimental hemochromatosis.

R A Melo1, A B Garcia, S R Viana, R P Falcão.   

Abstract

The distribution of lymphocyte subsets in blood, thymus, spleen, mesenteric lymph nodes, Peyer's patches and bone marrow was evaluated in an experimental model of secondary hemochromatosis in rats. The values of CD2, CD4, CD8, B and NK cells in these different lymphoid compartments did not differ between the control group and the experimental group. These results suggest that the abnormalities of lymphocyte subsets previously reported in patients with secondary hemochromatosis may be due to factors other than iron overload.

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Year:  1997        PMID： 9286302     DOI： 10.1159/000203595

Source DB:  PubMed          Journal:  Acta Haematol        ISSN： 0001-5792            Impact factor:   2.195


  3 in total

Review 1.  Iron and immunity: immunological consequences of iron deficiency and overload.

Authors:  Bobby J Cherayil
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2010-09-28       Impact factor: 4.291

2.  Total blood lymphocyte counts in hemochromatosis probands with HFE C282Y homozygosity: relationship to severity of iron overload and HLA-A and -B alleles and haplotypes.

Authors:  James C Barton; Ronald T Acton; Howard W Wiener; Rodney Cp Go
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3.  The novel SLC40A1 (T419I) variant results in a loss-of-function phenotype and may provide insights into the mechanism of large granular lymphocytic leukemia and pure red cell aplasia.

Authors:  Hongfei Wu; Xiang Ren; Meili Ge; Peiyuan Dong; Shichong Wang; Huiming Yi; Xingxin Li; Jiali Huo; Xuan Zheng; Mengying Gao; Jinbo Huang; Jing Zhang; Min Wang; Peng Jin; Neng Nie; Yingqi Shao; Yizhou Zheng
Journal:  Blood Sci       Date:  2021-12-06
  3 in total

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