| Literature DB >> 9285700 |
Abstract
Recent results show that the 8-oxoguanine DNA repair system is functionally conserved in bacteria and mammals. The bacterial system protects the genome from the mutagenic effects of oxidative stress; the role of the mammalian system is expected to be similar and defects in it may increase susceptibility to cancer.Entities:
Mesh:
Year: 1997 PMID: 9285700 DOI: 10.1016/s0960-9822(06)00286-7
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834