Literature DB >> 9284575

[Evaluation of cytokine production in leprosy patients].

S Fink1, M R Finiasz, R Valdez, S de la Barrera, M C Sasiain.   

Abstract

The aim of the present study was to evaluate the cytokine production by peripheral blood mononuclear cells (PBMC) of leprosy patients when the cells were stimulated in culture by ConA, PPD or M.leprae. We measured IL-2, IL-4, IFN-gamma and IL-6 in cell-free supernatants by enzyme linked immunoassays. Our results do not suggest a clear association of a clinical form of leprosy with either Th1 or Th2 cytokine secretion profile in PBMC of leprosy patients.

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Year:  1996        PMID： 9284575

Source DB:  PubMed          Journal:  Medicina (B Aires)        ISSN： 0025-7680            Impact factor:   0.653


  2 in total

1.  Interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) are necessary in the early stages of induction of CD4 and CD8 cytotoxic T cells by Mycobacterium leprae heat shock protein (hsp) 65 kD.

Authors:  M C Sasiain; S de la Barrera; S Fink; M Finiasz; M Alemán; M H Fariña; G Pizzariello; R Valdez
Journal:  Clin Exp Immunol       Date:  1998-11       Impact factor: 4.330

2.  The Effects of Prednisolone Treatment on Cytokine Expression in Patients with Erythema Nodosum Leprosum Reactions.

Authors:  Edessa Negera; Stephen L Walker; Kidist Bobosha; Yonas Bekele; Birtukan Endale; Azeb Tarekegn; Markos Abebe; Abraham Aseffa; Hazel M Dockrell; Diana N Lockwood
Journal:  Front Immunol       Date:  2018-02-09       Impact factor: 7.561
  2 in total

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