Literature DB >> 928431

Genetic factors in the development of atheroma and on serum total cholesterol levels in inbred mice and their hybrids.

A Roberts, J S Thompson.   

Abstract

There is a consistent genetic relationship between the development of atheromata in the aortic sinus wall and serum total cholesterol levels using inbred strains of male mice. This relationship is dependent on a multifactorial (polygenic) type of inheritance that is more complicated than the simple additive-dominance model. There is no special maternal or paternal influence on serum total cholesterol levels or on the development of atheromata.

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Year:  1977        PMID： 928431

Source DB:  PubMed          Journal:  Prog Biochem Pharmacol        ISSN： 0079-6085


  7 in total

1.  Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model.

Authors:  C L Welch; S Bretschger; N Latib; M Bezouevski; Y Guo; N Pleskac; C P Liang; C Barlow; H Dansky; J L Breslow; A R Tall
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-03       Impact factor: 11.205

2.  Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor-/- mice.

Authors:  Daniel Teupser; Marietta Tan; Adam D Persky; Jan L Breslow
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-27       Impact factor: 11.205

3.  Regulation of polyunsaturated fat induced postprandial hypercholesterolemia by a novel gene Phc-2.

Authors:  D S Vaithilingam; V Antao; G Kakis
Journal:  Mol Cell Biochem       Date:  1994-01-12       Impact factor: 3.396

4.  Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice.

Authors:  B Paigen; D Mitchell; K Reue; A Morrow; A J Lusis; R C LeBoeuf
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

5.  Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility.

Authors:  B Paigen; D Albee; P A Holmes; D Mitchell
Journal:  Biochem Genet       Date:  1987-08       Impact factor: 1.890

6.  Dietary resveratrol increases the expression of hepatic 7α-hydroxylase and ameliorates hypercholesterolemia in high-fat fed C57BL/6J mice.

Authors:  Qiong Chen; Ermao Wang; Liping Ma; Pei Zhai
Journal:  Lipids Health Dis       Date:  2012-05-20       Impact factor: 3.876

Review 7.  The Microbial Metabolite Trimethylamine N-Oxide Links Vascular Dysfunctions and the Autoimmune Disease Rheumatoid Arthritis.

Authors:  Marion M Chan; Xiaofeng Yang; Hong Wang; Fatma Saaoud; Yu Sun; Dunne Fong
Journal:  Nutrients       Date:  2019-08-07       Impact factor: 5.717
  7 in total

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