Literature DB >> 9284174

Allelic variation in Streptococcus pneumoniae autolysin (N-acetyl muramoyl-L-alanine amidase).

S H Gillespie1, T D McHugh, H Ayres, A Dickens, A Efstratiou, G C Whiting.   

Abstract

The lytA gene encoding the autolysin of Streptococcus pneumoniae may be a virulence determinant. Single-strand conformational polymorphism analysis demonstrated heterogenicity throughout the gene in clinical isolates and strains from the clonal serotypes 7 and 14. Sequence analysis of part of the choline-binding domain showed that in two isolates four amino acid substitutions occurred.

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Year:  1997        PMID： 9284174      PMCID： PMC175561          DOI： 10.1128/iai.65.9.3936-3938.1997

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  16 in total

1.  The nature of cell wall-derived inflammatory components of pneumococci.

Authors:  A Tomasz; K Saukkonen
Journal:  Pediatr Infect Dis J       Date:  1989-12       Impact factor: 2.129

2.  Protein-bound choline is released from the pneumococcal autolytic enzyme during adsorption of the enzyme to cell wall particles.

Authors:  Z Markiewicz; A Tomasz
Journal:  J Bacteriol       Date:  1990-05       Impact factor: 3.490

3.  Purification and characterization of the autolytic glycosidase of Streptococcus pneumoniae.

Authors:  P García; J L García; E García; R López
Journal:  Biochem Biophys Res Commun       Date:  1989-01-16       Impact factor: 3.575

4.  Molecular characterization of an autolysin-defective mutant of Streptococcus pneumoniae.

Authors:  J L García; J M Sánchez-Puelles; P García; R López; C Ronda; E García
Journal:  Biochem Biophys Res Commun       Date:  1986-06-13       Impact factor: 3.575

5.  Nucleotide sequence and expression of the pneumococcal autolysin gene from its own promoter in Escherichia coli.

Authors:  P García; J L García; E García; R López
Journal:  Gene       Date:  1986       Impact factor: 3.688

6.  Sequence variation in the Streptococcus pneumoniae pneumolysin gene affecting haemolytic activity and electrophoretic mobility of the toxin.

Authors:  R A Lock; Q Y Zhang; A M Berry; J C Paton
Journal:  Microb Pathog       Date:  1996-08       Impact factor: 3.738

7.  Induction of pulmonary inflammation by components of the pneumococcal cell surface.

Authors:  E Tuomanen; R Rich; O Zak
Journal:  Am Rev Respir Dis       Date:  1987-04

8.  Biological role of the pneumococcal amidase. Cloning of the lytA gene in Streptococcus pneumoniae.

Authors:  C Ronda; J L García; E García; J M Sánchez-Puelles; R López
Journal:  Eur J Biochem       Date:  1987-05-04

9.  Differences of pathophysiology in experimental meningitis caused by three strains of Streptococcus pneumoniae.

Authors:  M G Täuber; M Burroughs; U M Niemöller; H Kuster; U Borschberg; E Tuomanen
Journal:  J Infect Dis       Date:  1991-04       Impact factor: 5.226

10.  Subtyping of common pediatric pneumococcal serotypes from invasive disease and pharyngeal carriage in Finland.

Authors:  A K Takala; J Vuopio-Varkila; E Tarkka; M Leinonen; J M Musser
Journal:  J Infect Dis       Date:  1996-01       Impact factor: 5.226
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  6 in total

1.  Loop-mediated isothermal amplification method targeting the lytA gene for detection of Streptococcus pneumoniae.

Authors:  Mitsuko Seki; Yoshihisa Yamashita; Hirotaka Torigoe; Hiromasa Tsuda; Setsuko Sato; Masao Maeno
Journal:  J Clin Microbiol       Date:  2005-04       Impact factor: 5.948

2.  The autolysin-encoding gene (lytA) of Streptococcus pneumoniae displays restricted allelic variation despite localized recombination events with genes of pneumococcal bacteriophage encoding cell wall lytic enzymes.

Authors:  A M Whatmore; C G Dowson
Journal:  Infect Immun       Date:  1999-09       Impact factor: 3.441

3.  Characterization of mutants deficient in the L,D-carboxypeptidase (DacB) and WalRK (VicRK) regulon, involved in peptidoglycan maturation of Streptococcus pneumoniae serotype 2 strain D39.

Authors:  Skye M Barendt; Lok-To Sham; Malcolm E Winkler
Journal:  J Bacteriol       Date:  2011-03-04       Impact factor: 3.490

4.  Sensitive and specific method for rapid identification of Streptococcus pneumoniae using real-time fluorescence PCR.

Authors:  J C McAvin; P A Reilly; R M Roudabush; W J Barnes; A Salmen; G W Jackson; K K Beninga; A Astorga; F K McCleskey; W B Huff; D Niemeyer; K L Lohman
Journal:  J Clin Microbiol       Date:  2001-10       Impact factor: 5.948

5.  Characterization of Ejl, the cell-wall amidase coded by the pneumococcal bacteriophage Ej-1.

Authors:  José L Sáiz; Consuelo López-Zumel; Begoña Monterroso; Julio Varea; José Luis R Arrondo; Ibon Iloro; José L García; José Laynez; Margarita Menéndez
Journal:  Protein Sci       Date:  2002-07       Impact factor: 6.725

Review 6.  Choline Binding Proteins from Streptococcus pneumoniae: A Dual Role as Enzybiotics and Targets for the Design of New Antimicrobials.

Authors:  Beatriz Maestro; Jesús M Sanz
Journal:  Antibiotics (Basel)       Date:  2016-06-14
  6 in total

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