Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effect of estradiol metabolites on the susceptibility of low density lipoprotein to oxidation.

Literature DB >> 9284079

Effect of estradiol metabolites on the susceptibility of low density lipoprotein to oxidation.

Abstract

The main estradiol metabolites 2-hydroxyestrone, 2-methoxyestrone and 16alpha-hydroxyestrone were investigated in vitro for the susceptibility of low density lipoprotein to oxidation and the effects compared with those of estradiol and vitamin E. 2-hydroxyestrone and 2-methoxyestrone had a greater inhibitory effect than estradiol and vitamin E whereas 16alpha-hydroxyestrone approximates the inhibition of estradiol. These results indicate that 2-hydroxyestrone and 2-methoxyestrone possess non-genomic actions which may play a role in the lipid metabolism.

Entities: Chemical

Mesh：

Substances：

Year: 1997 PMID： 9284079 DOI： 10.1016/s0024-3205(97)00588-2

Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037

Keyword Cloud
Cited

8 in total

Review 1. Impact of sex hormone metabolism on the vascular effects of menopausal hormone therapy in cardiovascular disease.

Authors: Durr-e-Nayab Masood; Emir C Roach; Katie G Beauregard; Raouf A Khalil
Journal: Curr Drug Metab Date: 2010-10 Impact factor: 3.731

2. Dietary fiber and serum 16α-hydroxyestrone, an estrogen metabolite associated with lower systolic blood pressure.

Authors: Shawn Patel; Louise C Hawkley; John T Cacioppo; Christopher M Masi
Journal: Nutrition Date: 2010-10-29 Impact factor: 4.008

3. 2-Methoxyestradiol Reduces Angiotensin II-Induced Hypertension and Renal Dysfunction in Ovariectomized Female and Intact Male Mice.

Authors: Ajeeth K Pingili; Karen N Davidge; Shyamala Thirunavukkarasu; Nayaab S Khan; Akemi Katsurada; Dewan S A Majid; Frank J Gonzalez; L Gabriel Navar; Kafait U Malik
Journal: Hypertension Date: 2017-04-17 Impact factor: 10.190

4. Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress.

Authors: MaryFran Sowers; Daniel McConnell; Mary L Jannausch; John F Randolph; Robert Brook; Ellen B Gold; Sybil Crawford; Bill Lasley
Journal: Clin Endocrinol (Oxf) Date: 2007-11-02 Impact factor: 3.478

5. Levels of sex steroid and cardiovascular disease measures in premenopausal and hormone-treated women at midlife: implications for the "timing hypothesis".

Authors: MaryFran R Sowers; John Randolph; Mary Jannausch; Bill Lasley; Elizabeth Jackson; Daniel McConnell
Journal: Arch Intern Med Date: 2008-10-27

Effect of estradiol metabolites on the susceptibility of low density lipoprotein to oxidation.

Review 1. Impact of sex hormone metabolism on the vascular effects of menopausal hormone therapy in cardiovascular disease.

2. Dietary fiber and serum 16α-hydroxyestrone, an estrogen metabolite associated with lower systolic blood pressure.

3. 2-Methoxyestradiol Reduces Angiotensin II-Induced Hypertension and Renal Dysfunction in Ovariectomized Female and Intact Male Mice.

4. Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress.

5. Levels of sex steroid and cardiovascular disease measures in premenopausal and hormone-treated women at midlife: implications for the "timing hypothesis".

6. Serum estrogen metabolites and systolic blood pressure among middle-aged and older women and men.

7. 2-Methoxyestradiol protects against pressure overload-induced left ventricular hypertrophy.

8. Urinary estrogen levels in women on contraceptives in enugu, South-East Nigeria.