Literature DB >> 9279653

Articular cartilage chondrons: form, function and failure.

C A Poole1.   

Abstract

The chondrocyte and its pericellular microenvironment together represent the chondron, historically considered the primary structural, functional and metabolic unit of articular and other hyaline cartilages. This review summarises research over the last 10 years to establish the molecular anatomy, functional properties and metabolic contribution of the chondron in articular cartilage homeostasis, and its failure during the initiation and progression of degenerative osteoarthritis.

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Year:  1997        PMID: 9279653      PMCID: PMC1467653          DOI: 10.1046/j.1469-7580.1997.19110001.x

Source DB:  PubMed          Journal:  J Anat        ISSN: 0021-8782            Impact factor:   2.610


  30 in total

Review 1.  The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules.

Authors:  H Muir
Journal:  Bioessays       Date:  1995-12       Impact factor: 4.345

Review 2.  Recent advances in the biochemistry of hyaluronic acid in cartilage.

Authors:  R M Mason
Journal:  Prog Clin Biol Res       Date:  1981

3.  Sequestration of type VI collagen in the pericellular microenvironment of adult chrondrocytes cultured in agarose.

Authors:  J Chang; C A Poole
Journal:  Osteoarthritis Cartilage       Date:  1996-12       Impact factor: 6.576

4.  Morphological and functional interrelationships of articular cartilage matrices.

Authors:  C A Poole; M H Flint; B W Beaumont
Journal:  J Anat       Date:  1984-01       Impact factor: 2.610

5.  Chondrons in cartilage: ultrastructural analysis of the pericellular microenvironment in adult human articular cartilages.

Authors:  C A Poole; M H Flint; B W Beaumont
Journal:  J Orthop Res       Date:  1987       Impact factor: 3.494

6.  Detection of viable and non-viable cells in connective tissue explants using the fixable fluoroprobes 5-chloromethylfluorescein diacetate and ethidium homodimer-1.

Authors:  C A Poole; N H Brookes; R T Gilbert; B W Beaumont; A Crowther; L Scott; M J Merrilees
Journal:  Connect Tissue Res       Date:  1996       Impact factor: 3.417

7.  Identification and immunolocalization of laminin in cartilage.

Authors:  J Dürr; P Lammi; S L Goodman; T Aigner; K von der Mark
Journal:  Exp Cell Res       Date:  1996-01-10       Impact factor: 3.905

8.  Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

Authors:  T T Glant; C Hadházy; K Mikecz; A Sipos
Journal:  Histochemistry       Date:  1985

9.  A study of the structural response of wet hyaline cartilage to various loading situations.

Authors:  N D Broom; D B Myers
Journal:  Connect Tissue Res       Date:  1980       Impact factor: 3.417

10.  A functional-morphological study of the tidemark region of articular cartilage maintained in a non-viable physiological condition.

Authors:  N D Broom; C A Poole
Journal:  J Anat       Date:  1982-08       Impact factor: 2.610

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  92 in total

1.  Immunofluorescence-guided atomic force microscopy to measure the micromechanical properties of the pericellular matrix of porcine articular cartilage.

Authors:  Rebecca E Wilusz; Louis E DeFrate; Farshid Guilak
Journal:  J R Soc Interface       Date:  2012-06-06       Impact factor: 4.118

2.  Biomechanical properties of single chondrocytes and chondrons determined by micromanipulation and finite-element modelling.

Authors:  Bac V Nguyen; Qi Guang Wang; Nicola J Kuiper; Alicia J El Haj; Colin R Thomas; Zhibing Zhang
Journal:  J R Soc Interface       Date:  2010-06-02       Impact factor: 4.118

Review 3.  Cartilage cell clusters.

Authors:  Martin K Lotz; Shuhei Otsuki; Shawn P Grogan; Robert Sah; Robert Terkeltaub; Darryl D'Lima
Journal:  Arthritis Rheum       Date:  2010-08

4.  The Impact of Collagen Fibril Polarity on Second Harmonic Generation Microscopy.

Authors:  Charles-André Couture; Stéphane Bancelin; Jarno Van der Kolk; Konstantin Popov; Maxime Rivard; Katherine Légaré; Gabrielle Martel; Hélène Richard; Cameron Brown; Sheila Laverty; Lora Ramunno; François Légaré
Journal:  Biophys J       Date:  2015-12-15       Impact factor: 4.033

5.  In vitro culture of enzymatically isolated chondrons: a possible model for the initiation of osteoarthritis.

Authors:  J M Ross; A F Sherwin; C A Poole
Journal:  J Anat       Date:  2006-12       Impact factor: 2.610

6.  A numerical study to determine pericellular matrix modulus and evaluate its effects on the micromechanical environment of chondrocytes.

Authors:  Arthur J Michalek; James C Iatridis
Journal:  J Biomech       Date:  2006-07-25       Impact factor: 2.712

7.  Snapshot of degenerative aging of porcine intervertebral disc: a model to unravel the molecular mechanisms.

Authors:  Hongsik Cho; Sang Hyug Park; Sangmin Lee; Miji Kang; Karen A Hasty; Song Ja Kim
Journal:  Exp Mol Med       Date:  2011-06-30       Impact factor: 8.718

8.  Communication between paired chondrocytes in the superficial zone of articular cartilage.

Authors:  Simon S Chi; Jerome B Rattner; John R Matyas
Journal:  J Anat       Date:  2004-11       Impact factor: 2.610

9.  Protein Levels and Microstructural Changes in Localized Regions of Early Cartilage Degeneration Compared with Adjacent Intact Cartilage.

Authors:  Bincy Jacob; Mia Jüllig; Martin Middleditch; Leo Payne; Neil Broom; Vijayalekshmi Sarojini; Ashvin Thambyah
Journal:  Cartilage       Date:  2018-11-28       Impact factor: 4.634

10.  ADAMTS9 activation by interleukin 1 beta via NFATc1 in OUMS-27 chondrosarcoma cells and in human chondrocytes.

Authors:  Kursat Oguz Yaykasli; Toshitaka Oohashi; Satoshi Hirohata; Omer Faruk Hatipoglu; Kiichi Inagawa; Kadir Demircan; Yoshifumi Ninomiya
Journal:  Mol Cell Biochem       Date:  2008-12-04       Impact factor: 3.396

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