N G Ordóñez1, E G Silva. 1. University of Texas M.D. Anderson Cancer Centre, Houston 77030, USA.
Abstract
AIMS: A previously unreported clear cell variant of islet cell tumour of the pancreas is described. METHODS AND RESULTS: By light microscopy, the cytoplasm of the clear cells was finely reticulated and vacuolated. Immuno-histochemical and electron microscopy studies confirmed the endocrine nature of the tumour. CONCLUSIONS: The clear cell morphology was due to the accumulation of lipid in the cytoplasm.
AIMS: A previously unreported clear cell variant of islet cell tumour of the pancreas is described. METHODS AND RESULTS: By light microscopy, the cytoplasm of the clear cells was finely reticulated and vacuolated. Immuno-histochemical and electron microscopy studies confirmed the endocrine nature of the tumour. CONCLUSIONS: The clear cell morphology was due to the accumulation of lipid in the cytoplasm.